Zhu L, Cheng J, Xiao F, Mao YY. Effects of comprehensive nutrition support on immune function, wound healing, hospital stay, and mental health in gastrointestinal surgery. World J Gastrointest Surg 2024; 16(12): 3737-3744 [DOI: 10.4240/wjgs.v16.i12.3737]
Corresponding Author of This Article
Ling Zhu, BM BCh, Nurse, Department of Gastrointestinal Surgery, Wuhan Fourth Hospital, Gutian Third Road, Qiaokou District, Wuhan 430000, Hubei Province, China. lingzhu901118@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Dec 27, 2024; 16(12): 3737-3744 Published online Dec 27, 2024. doi: 10.4240/wjgs.v16.i12.3737
Table 1 Comparison of general data between the two groups, n (%)
Index
Experimental group (n = 30)
Control group (n = 30)
t/F
P value
Age (years)
48.38 ± 9.18
52.94 ± 9.73
-1.87
0.07
Sex (male/female)
18/12
17/13
0.26
0.80
BMI (kg/m²)
23.02 ± 2.89
23.89 ± 3.21
-1.10
0.28
Type of operation
Stomach cancer: 20; colon cancer: 10
Stomach cancer: 18; colon cancer: 12
-3.27
0.58
Underlying disease
12 (40)
14 (46.7)
2.17
0.62
Table 2 Comparison of immune function indexes on the seventh day after surgery between the two groups
Index
Experimental group (n = 30)
Control group (n = 30)
t
P value
White blood cell count (× 109/L)
8.52 ± 1.19
6.74 ± 1.31
5.51
< 0.05
CD4+ T cell ratio (%)
40.09 ± 4.91
33.01 ± 5.08
5.49
< 0.05
CD8+ T cell ratio (%)
21.79 ± 3.38
26.29 ± 3.09
-5.38
< 0.05
CD4+/CD8+ ratio
1.91 ± 0.32
1.13 ± 0.23
11.00
< 0.05
Table 3 Comparison of wound healing between the two groups, n (%)
Index
Experimental group (n = 30)
Control group (n = 30)
t
P value
Wound infection rate
3 (10)
9 (30)
-3.62
< 0.05
Wound healing time (days)
10.35 ± 2.42
14.42 ± 3.15
-5.62
< 0.05
Table 4 Comparison of pain score (visual analog scale) and length of stay between the two groups
Index
Experimental group (n = 30)
Control group (n = 30)
t
P value
VAS score on day 3 after surgery
3.05 ± 1.04
5.11 ± 1.09
-7.12
< 0.05
VAS score on the 7th day after surgery
2.19 ± 0.93
4.43 ± 1.05
-8.80
< 0.05
Length of stay (days)
16.16 ± 3.12
20.93 ± 4.84
-4.53
< 0.05
Table 5 Comparison of psychological status scores between the two groups
Index
Experimental group (n = 30)
Control group (n = 30)
t
P value
HAMA score
8.88 ± 1.87
12.1 ± 3.27
-4.69
< 0.05
HAMD score
7.37 ± 1.41
11.79 ± 2.77
-7.79
< 0.05
Citation: Zhu L, Cheng J, Xiao F, Mao YY. Effects of comprehensive nutrition support on immune function, wound healing, hospital stay, and mental health in gastrointestinal surgery. World J Gastrointest Surg 2024; 16(12): 3737-3744