Micro-power negative pressure wound technique reduces risk of incision infection following loop ileostomy closure

Table 1 Demographic and clinical features of included patients

Variable	Control group (n = 51)	MPNPWT group (n = 50)	P value
Gender, n (%)			0.487
Male	34 (66.7)	30 (60.0)
Female	17 (33.3)	20 (40.0)
Age (yr)	64.43 ± 9.06	61.66 ± 14.22	0.247
BMI (kg/m2)	21.82 ± 2.90	22.61 ± 3.06	0.184
Hypertension, n (%)	22 (43.1)	19 (38.0)	0.599
Diabetes, n (%)	7 (13.7)	8 (16.0)	0.748
ASA score, n (%)			0.362
1-2	50 (98.0)	47 (94.0)
3	1 (2.0)	3 (6.0)
HB (g/L)	130.78 ± 14.67	132.36 ± 13.32	0.573
Albumin (g/L)	43.10 ± 4.00	43.95 ± 3.75	0.275
Perioperative, n (%), CRT	32 (62.7)	27 (54.0)	0.373
Parastomal hernia, n (%)	7 (13.7)	5 (10.0)	0.563
Time duration from ileostomy to closure (mo)	6.13 ± 2.45	5.51 ± 2.67	0.232

MPNPWT: Micro-power negative pressure wound technique; BMI: Body mass index; HB: Hemoglobin; CRT: Chemoradiotherapy.

Table 2 Surgical outcomes of included patients

Variable	Control group (n = 51)	MPNPWT group (n = 50)	P value
Operative time (min)	78.14 ± 20.02	81.36 ± 17.64	0.393
Blood loss (mL)	17.35 ± 4.40	19.70 ± 7.45	0.056
Complications, n (%)
Anastomotic inflammation	3 (5.9)	0 (0.0)	0.243
Bowel obstruction	3 (5.9)	5 (10.0)	0.487
Incisional SSI, n (%)	8 (15.7)	1 (2.0)	0.031
Postoperative hospital stays (d)	8.51 ± 4.03	7.34 ± 2.06	0.069
Hospitalization costs (yuan)	26168.84 ± 6627.74	26419.4 ± 6019.23	0.843

MPNPWT: Micro-power negative pressure wound technique; SSI: Surgical site infection.

Table 3 Logistic analysis of risk factors for surgical site infection

Variable	Univariate		Multivariate
	OR (95%CI)	P value	OR (95%CI)	P value
Female gender	0.465 (0.091–2.367)	0.357
Age (yr)	1.034 (0.965–1.107)	0.343
BMI (kg/m2)	1.115 (0.929–1.337)	0.241
ASA score 3	3.708 (0.345–39.908)	0.28
Hypertension	3.257 (0.765–13.863)	0.11
Diabetes	5.891 (1.371–25.311)	0.017	26.575 (1.391–507.694)	0.029
HB (g/L)	0.967 (0.921–1.016)	0.189
Albumin (g/L)	1.053 (0.883–1.254)	0.567
MPNPWT	0.110 (0.013–0.913)	0.041	0.005 (0.000–0.515)	0.025
Perioperative CRT	0.880 (0.222–3.492)	0.855
Blood loss (mL)	1.010 (0.910–1.122)	0.849
Operative time (min)	1.007 (0.973–1.043)	0.677

ASA: American Society of Anaesthesiology; MPNPWT: Micro-power negative pressure wound technique; BMI: Body mass index; HB: Hemoglobin; CRT: Chemoradiotherapy; OR: Odds ratio; 95%CI: 95% confidence interval.