Published online Jan 27, 2024. doi: 10.4240/wjgs.v16.i1.186
Peer-review started: August 22, 2023
First decision: November 20, 2023
Revised: November 30, 2023
Accepted: December 13, 2023
Article in press: December 13, 2023
Published online: January 27, 2024
Although ileostomy closure is technically easy, it is associated with a non-negligible overall morbidity rate (11%-37%), with incisional surgical site infection (SSI) being the most common.
The incisional SSI rate after ileostomy closure is much higher than those of other intestinal surgeries, ranging from 2% to 40%. Incisional SSI is responsible for increased pain, longer hospital stays, and higher treatment costs. Current methods for incisional SSI prevention have limitations. Finding a new approach to prevent incisional SSI is urgent for patients receiving ileostomy closure.
Micro-power negative pressure wound technique (MPNPWT) contains a special material that produces micro-negative pressure by absorbing exudates rather than suction device. It reduces wound edema and stimulates epithelial cell proliferation and granulation tissue growth, thus shortening wound healing time. This study aimed to evaluate the efficacy and safety of MPNPWT in preventing incisional SSI. The results of our study will provide foundation for future application of MPNPWT.
This was a single-center, prospective, randomized controlled trial (RCT). An independent statistician randomly assigned eligible patients in a 1:1 ratio using sequentially sealed envelopes to a control group or an MPNPWT group without stratification. Micro-power negative pressure dressing was filled on the skin surface of patients in the MPNPWT group by nurses from wound care clinic.
MPNPWT significantly reduced incisional SSI rate (2.0%). MPNPWT is a safe technique without any side effect. MPNPWT could also help heal the infected incision.
Our study introduces a novel technique, MPNPWT, to prevent incisional SSI after loop ileostomy closure. MPNPWT reduces the incidence of incisional SSI after loop ileostomy closure.
A larger RCT with a larger sample is the direction of the future research.