Effects of remifentanil combined with propofol on hemodynamics and oxidative stress in patients undergoing resection of rectal carcinoma

Table 1 Baseline data

Factors	Remifentanil group (n = 45)	Sufentanil group (n = 59)	χ2 value	P value
Sex			0.035	0.850
Male	26	33
Female	19	26
Age			0.373	0.541
< 60 yr old	24	35
≥ 60 yr old	21	24
BMI			0.148	0.700
≥ 25 kg/m2	20	24
< 25 kg/m2	25	35
ASA classification			3.141	0.208
I	21	18
II	22	39
III	2	2
History of diabetes mellitus			3.083	0.079
Yes	17	13
No	28	46
History of hypertension			1.590	0.207
Yes	40	47
No	5	12
History of smoking			0.035	0.850
Yes	26	33
No	19	26

ASA: American society of anesthesiologists; BMI: Body mass index.

Table 2 Comparison of general data

Group	Operation time	Anesthesia time	Extubation time
Remifentanil group (n = 45)	2.76 ± 0.44	3.25 ± 0.89	12.95 ± 3.49
Sufentanil group (n = 59)	2.94 ± 0.49	3.49 ± 0.95	13.71 ± 3.67
t value	1.942	1.312	1.059
P value	0.055	0.192	0.292

Table 3 The consumption of remifentanil and the use of vasoactive drugs during surgery

Indices	Remifentanil group (n = 45)	Sufentanil group (n = 59)	χ2/t	P value
Consumption of remifentanil (μg/kg/h)	2.68 ± 0.51	3.89 ± 1.10	6.881	< 0.001
Adoption frequency of ephedrine	10	31	9.827	0.002
Adoption frequency of atropine	11	7	2.823	0.092

Table 4 Adverse reactions

Group	Nausea and vomiting	Choking cough	Hypotension	Bradycardia
Remifentanil group (n = 45)	3	1	10	8
Sufentanil group (n = 59)	5	2	30	18
χ2 value	0.117	0.124	8.838	2.207
P value	0.731	0.724	0.002	0.137