Retrospective Study
Copyright ©The Author(s) 2023.
World J Gastrointest Surg. Nov 27, 2023; 15(11): 2482-2489
Published online Nov 27, 2023. doi: 10.4240/wjgs.v15.i11.2482
Table 1 Baseline characteristics of the control and intervention groups (mean ± SE)
Variant
Control group (n = 110)
Intervention group (n = 110)
P value
Age (yr)28-63 (51.2 ± 1.3)36-68 (52.4 ± 1.0)0.488
Sex [cases (%)]
    Males25 (22.73)27 (24.55)0.605
    Females85 (77.27)83 (75.45)
Weight (kg)67.7 ± 1.769.2 ± 1.60.526
Height (cm)170.7 ± 1.4172.4 ± 1.30.385
BMI (kg/m2)25.1 ± 0.425.1 ± 0.40.959
SBP (mmHg)141.4 ± 1.4141.9 ± 1.40.788
DBP (mmHg)89.7 ± 1.589.5 ± 1.70.913
MDA (nmol/L)4.24 ± 1.74.74 ± 1.50.196
GSH (μmol/L)7.95 ± 3.26.93 ± 3.40.251
SOD (U/mL)74.21 ± 12.367.66 ± 13.40.051
Heart rate (time/min)78.1 ± 1.678.9 ± 1.30.693
1Educational level3:16:164:18:140.827
2Monthly household income8:14:136:15:150.799
Table 2 Post-intervention changes in the blood pressure between the intervention and control groups (mean ± SE)
Norm
Control subjects
Intervention group
P value
DBP (mmHg)Start of intervention 86.4 ± 1.483.9 ± 1.70.241
End of intervention 82.8 ± 1.676.6 ± 1.60.007
Amount of change before and after intervention3.6 ± 1.17.3 ± 1.10.000
SBP (mmHg)Start of intervention 137.3 ± 1.4133.2 ± 1.10.021
End of intervention131.1 ± 1.6116.3 ± 1.50.000
Amount of change before and after intervention6.2 ± 2.016.9 ± 1.40.022
Table 3 Nutrient intake in the control and intervention groups (mean ± SE)
Original proposal
Control subjects
Intervention group
P value
Energy (kcal)2033.74 ± 19.451953.01 ± 18.550.036
Fat (g)94.21 ± 1.1350.79 ± 0.750.001
Protein (g)76.42 ± 0.9797.72 ± 0.890.017
Carbohydrates (g)226.79 ± 3.29275.03 ± 4.210.029
Dietary fiber (g)10.28 ± 0.1125.22 ± 1.590.005
Cholesterol (mg)554.96 ± 3.84473.30 ± 7.330.012
SFA (g)47.58 ± 1.2127.83 ± 0.280.006
MUFA (g)29.5 ± 0.3712.44 ± 0.100.001
PUFA (g)20.20 ± 0.2112.34 ± 0.280.013
Sodium (mg)4347.28 ± 46.342284.86 ± 12.430.001
Potassium (mg)1663.15 ± 11.143088.78 ± 67.370.001
Calcium (mg)483.84 ± 14.09864.32 ± 21.600.001
Magnesium (mg)259.97 ± 2.28479.05 ± 14.120.014
Table 4 Comparison of the levels of oxidative stress indicators between the intervention and control groups (mean ± SE)
Norm
Control subjects
Intervention group
P value
ALT (nmol/L)End of intervention115.29 ± 1.263.94 ± 1.40.001
Amount of change before and after intervention21.25 ± 0.220.6 ± 0.10.015
AST (μmol/L)End of intervention157.15 ± 3.559.00 ± 2.80.017
Amount of change before and after intervention20.6 ± 0.222.17 ± 0.10.021
Table 5 Logistic multifactorial regression analysis of factors affecting the occurrence of extradigestive complications in patients with obesity
Variables
β-value
SE value
Wald value
P value
OR value
95%CI
History of hypertension1.2960.4219.4700.0023.6541.601-8.343
TC high0.2260.1382.6850.1011.2540.957-1.643
TG high0.3050.2112.0910.1481.3560.897-2.051
HDL-C high-0.2470.1234.0020.0450.7810.613-0.995
LDL-C high0.9090.25412.787< 0.0012.4811.508-4.085
PECAM-1 high0.0700.01912.930< 0.0011.0731.032-1.114
GDF11 high-0.0080.0039.1990.0020.9920.987-0.997
FGF21 high0.0240.00713.062< 0.0011.0241.011-1.038
Table 6 Receiver operating characteristic curve analysis of the serum levels of platelet endothelial cell adhesion molecule-1, growth differentiation factor 11, and fibroblast growth factor 21 in predicting the occurrence of extradigestive complications in patients with obesity
Indicators
Cut-of value
AUC (95%CI)
Sensitivity
Specificity
Jordon index
PECAM-140 μg/L0.798 (0.595-0.974)0.8240.7440.568
GDF11650 μg/L0.716 (0.509 -0.929)0.7160.7330.449
FGF21160 ng/L0.813 (0.671-0.940)0.8110.7910.602
Tripartite0.909 (0.850-0.958)0.9190.8840.803