Observational Study
Copyright ©The Author(s) 2022.
World J Gastrointest Surg. Sep 27, 2022; 14(9): 997-1007
Published online Sep 27, 2022. doi: 10.4240/wjgs.v14.i9.997
Table 1 Clinical characteristics of patients
Patient
Age in yr
Sex
Primary tumour location
Histologic type of tumour
Differentiation
Clinical stage of primary tumour
Neoadjuvant therapy
Oesophagectomy
ypTNM
Synchronous and Metachronous Oligometastatic Disease
1162FemaleUpper thirdSCCModerateT4N1M1Walsh Regimen17NoNA
2253MaleOGJ ACPoorT3N2M1Walsh Regimen + CROSSYesT2bN1Mx
Synchronous Oligometastatic Disease Only
371MaleLower third/OGJACPoorT3N1M1Carbo5FU; 60GyYesT3N0M0
468MaleOGJACModerate-poorT3N2M0Walsh RegimenYesT2N0Mx
Metachronous Oligometastatic Disease Only
556MaleMiddle/lower thirdSCCModerateT3N2M0Walsh RegimenYesT2N1Mx
636MaleLowerACModerateT3N1M0CROSSYesT3N0Mx
73 72FemaleOGJACModerateT3N0M0CROSSYesT2N0
870MaleOGJACPoorNodal disease/Stage IIIAMAGICYesT2N1Mx
948MaleLower thirdACPoorStage IIBWalsh RegimenYesT1N0Mx
104 57MaleLower thirdACPoorT3N0M0CROSSYesT2N0M0
1160MaleOGJACPoorT3N0M0CROSSYesT0N0Mx
Table 2 Treatment of synchronous and metachronous oligometastatic oesophageal carcinoma
Patient
Synchronous metastases
Type
Treatment
Metachronous metastases
Type
Time to recurrence in mo
Treatment
Survival post recurrence in mo
Alive at study endpoint
Overall survival in mo
1YesLocally advanced1Walsh regimenYesLung 11.5Stereotactic radiotherapy36.4No47.9
2 YesCoeliac axisWalsh regimen + CROSS + radial gastrectomyYesLeft para-aortic nodes17.9Chemotherapy (Epirubicin, Oxaliplatin + Capecitabine)65.4Yes83.3
3YesLiverCarbo5FU; 60 Gy + oesophagectomyNoNANANANANo23.6
4YesLocally advanced2Walsh regimen + oesophagectomyNoNANANANAYes102.8
5 NoNANAYesLung32.9Left upper lobectomy (VATS)97.4No130.3
6NoNANAYesLung16.7Chemotherapy (carbo/taxol + FOLFOX)21.9No38.6
7NoNANAYesLung19.2Wedge resection (VATS)26.1No45.3
8 NoNANAYesAdrenal29.7Adrenalectomy62.1Yes91.8
9NoNANAYesAdrenal15.9Adrenalectomy + chemotherapy (irinotecan)118.9Yes134.8
10 NoNANAYesLiver33.0Resection + chemotherapy51.9Yes84.9
11 NoNANAYesParaaortic + Retroperitoneal15.7Chemotherapy (FOLFOX)14.9Yes30.6