Central pancreatectomy for benign or low-grade malignant pancreatic tumors in the neck and body of the pancreas

Table 1 Demographic and clinical characteristics of the patients

	Central pancreatectomy (n = 34)	Distal pancreatectomy (n = 262)	P value
Gender			0.627
Female, n (%)	25 (73.5)	182 (69.5)
Male, n (%)	9 (26.5)	80 (30.5)
Age (x ± s, yr)	48 ± 13	52 ± 15	0.172
BMI (x ± s, kg/m2)	22.4 ± 3.4	22.8 ± 3.6	0.545
Hypertension, n (%)	7 (20.6)	78 (29.8)	0.266
Diabetes, n (%)	2 (5.9)	28 (10.7)	0.568
Tumor size (x ± s, cm)	3.2 ± 1.8	3.5 ± 2.1	0.433
Pathology, n (%)			< 0.005
SCN	13 (38.2)	48 (18.3)
IPMN	4 (11.8)	47 (17.6)
MCN	1 (2.9)	50 (19.1)
SPN	13 (38.2)	52 (19.8)
pNET	3 (8.8)	50 (19.1)
Median distance between the tumor and left-side border of the SMV (mm)	8.9 (10.9)	12.5 (11.4)	0.076

BMI: Body mass index; SCN: Serous cystic neoplasm; IPMN: Intraductal papillary mucinous neoplasm; MCN: Mucinous cystic neoplasm; SPN: Solid pseudopapillary neoplasm; pNET: Pancreatic neuroendocrine tumor; SMV: Superior mesenteric vein.

Table 2 Perioperative outcomes of the patients

	Central pancreatectomy (n = 34)	Distal pancreatectomy (n = 262)	P value
Surgery, n (%)			< 0.005
Open surgery	25 (73.5)	63 (24.2)
Laparoscopy	9 (26.5)	197 (75.8)
Associated splenectomy, n (%)	0	123 (46.9)
Mean operation time (min)	311	244	< 0.05
Mean perioperative blood loss (mL)	159	167	0.525
Overall morbidity, n (%)			0.370
I	13 (38.2)	91 (34.0)
II	11 (32.4)	95 (36.6)
IIIa	2 (5.9)	17 (6.5)
IIIb	2 (5.9)	3 (1.1)
IV	0 (0)	0 (0)
POPF grade, n (%)			0.073
A	15 (44.1)	67 (25.6)
B	10 (29.4)	85 (32.4)
C	0 (0)	0 (0)
Chyle leakage, n (%)	1 (2.9)	15 (5.7)	0.926
Delayed gastric emptying, n (%)			< 0.05
A	9 (26.5)	38 (14.5)
B	1 (2.9)	2 (0.8)
C	0 (0)	1 (0.4)
Postoperative bleeding	0 (0)	0 (0)	-
Mean postoperative hospital stay (d)	17	11	0.783
In-hospital mortality	0 (0)	0 (0)	-
Readmission within 30 d	0 (0)	0 (0)	-

Data are presented as n (%), unless otherwise indicated. POPF: Postoperative pancreatic fistula.

Table 3 Endocrine and exocrine function of the pancreas after surgery

	Central pancreatectomy (n = 34)	Distal pancreatectomy (n = 262)	P value
Endocrine function
New-onset or aggravated diabetes mellitus, n (%)	0 (0)	40 (15.3)	< 0.05
Exocrine function
Diarrhea immediately after surgery	2 (5.9)	46 (17.6)	0.059
Diarrhea 12 mo after surgery	0 (0)	25 (9.5)	< 0.05

Data are presented as n (%).