Prognostic value of combined systemic inflammation response index and prognostic nutritional index in colorectal cancer patients

Figure 1 Area under the receiver operating characteristic curve of prognostic nutritional index and systemic inflammation response index. PNI: Prognostic nutritional index; SIRI: Systemic inflammation response index; ROC: Receiver operating characteristic; AUC: Area under receiver operating characteristic curve.

Figure 2 Cox regression analysis of prognostic nutritional index and systemic inflammation response index associated with overall survival. A: Prognostic nutritional index; B: Systemic inflammation response index. L-PNI: Low-prognostic nutritional index; H-PNI: High-prognostic nutritional index; SIRI: Systemic inflammation response index.

Figure 3 Area under the receiver operating characteristic curve of PSIRI and optimal cutoff values. AUC: Area under receiver operating characteristic curve.

Figure 4 Kaplan–Meier curves for overall survival of PSIRI. A: Categorized by PSIRI = 0, 1, 2; B: Categorized by PSIRI = 1, 2.

Figure 5 Stratification analysis of PSIRI in colorectal cancer. Adjusted for age, gender, BMI, smoke, drink, T stage, N stage, tumor stage, differentiated degree, nerve invasion, intravascular tumor emboli, carcinoembryonic antigen, neutrophil to lymphocyte ratio, monocyte to lymphocyte ratio, and platelet-to-lymphocyte ratio. SIRI: Systemic inflammation response index; BMI: Body mass index; CEA: Carcinoembryonic antigen; 95%CI: 95% confidence interval; HR: Hazard ratio.