Development and validation of a novel nomogram for predicting overall survival in gastric cancer based on inflammatory markers

Figure 1 The receiver operator characteristic curve of the blood markers. CEA: Carcinoembryonic antigen; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; PLT: Platelet; ROC: Receiver operator characteristic; SII: Systemic immune-inflammation index.

Figure 2 Nomogram for predicting overall survival after curative resection of gastric cancer. CEA: Carcinoembryonic antigen; OS: Overall survival; SII: Systemic immune-inflammation index; TNM: Tumor node metastasis.

Figure 3 Calibration curves. A: The prognostic nomogram for 3-year overall survival (OS) the training set; B: The prognostic nomogram for 5-year OS in the training set; C: The prognostic nomogram for 3-year OS in the validation set; D: The prognostic nomogram for 5-year OS in the validation set. OS: Overall survival.

Figure 4 The receiver operating characteristic curve of the prognostic nomogram in the training set. CEA: Carcinoembryonic antigen; SII: Systemic immune-inflammation index; TNM: Tumor node metastasis; ROC: Receiver operator characteristic.

Figure 5 Decision curve analysis. A: The decision curve analysis of the prognostic nomogram for predicting 3-year overall survival in the training set; B: The decision curve analysis of the prognostic nomogram for 5-year overall survival in the training set; C: The decision curve analysis of the prognostic nomogram for 3-year overall survival in the validation set; D: The decision curve analysis of the prognostic nomogram for 5-year overall survival in the validation set.

Figure 6 Survival curves stratified by the score calculated by the nomogram in the training cohort (low risk: < 60; intermediate risk: 60–120; and high risk: > 120).