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©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Feb 27, 2017; 9(2): 46-52
Published online Feb 27, 2017. doi: 10.4240/wjgs.v9.i2.46
Published online Feb 27, 2017. doi: 10.4240/wjgs.v9.i2.46
Perinatal risk factors in newborns with gastrointestinal perforation
Sandra Prgomet, Adela Arapović, Department of Pediatrics, University Hospital of Split and University of Split, School of Medicine, 21000 Split, Croatia
Boris Lukšić, Department of Infectious diseases, University Hospital of Split and University of Split, School of Medicine, 21000 Split, Croatia
Zenon Pogorelić, Ivo Jurić, Department of Pediatric Surgery, University Hospital of Split and University of Split, School of Medicine, 21000 Split, Croatia
Vesna Čapkun, Department of Nuclear Medicine, University Hospital of Split and University of Split, School of Medicine, 21000 Split, Croatia
Nataša Boban, Department of Clinical Epidemiology, University Hospital of Split and University of Split, School of Medicine, 21000 Split, Croatia
Author contributions: All the authors completely contributed to this paper.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of the University Hospital of Split.
Informed consent statement: Legal guardian of all study participants provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: All the Authors have no conflict of interest related to the manuscript.
Data sharing statement: The original anonymous dataset is available on request from the first author at sandra.skember.prgomet@gmail.com.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Zenon Pogorelić, MD, PhD, Associate Professor, Department of Pediatric Surgery, University Hospital of Split and University of Split, School of Medicine, Spinčićeva 1, 21000 Split, Croatia. zpogorelic@gmail.com
Telephone: +38-521-556182 Fax: +38-521-556724
Received: July 6, 2016
Peer-review started: July 9, 2016
First decision: October 20, 2016
Revised: November 10, 2016
Accepted: December 1, 2016
Article in press: December 2, 2016
Published online: February 27, 2017
Processing time: 232 Days and 22.6 Hours
Peer-review started: July 9, 2016
First decision: October 20, 2016
Revised: November 10, 2016
Accepted: December 1, 2016
Article in press: December 2, 2016
Published online: February 27, 2017
Processing time: 232 Days and 22.6 Hours
Core Tip
Core tip: Gastrointestinal perforation (GIP) in newborns is a severe and life threatening condition associated with high mortality. GIP usually occurs in prematures with necrotizing enterocolitis. GIP in newborns is mostly disease of infants with birth weight below 10th percentile according to gestational age. GIP occurs more often in infants with anemia. The most common site of perforation was large intestine Mortality rate was 31%. Infants with GIP more frequently had very low birth weight (< 1500 g), especially birth weight below 10th percentile according to gestational age.