Ziogas IA, Tsoulfas G. Advances and challenges in laparoscopic surgery in the management of hepatocellular carcinoma. World J Gastrointest Surg 2017; 9(12): 233-245 [PMID: 29359029 DOI: 10.4240/wjgs.v9.i12.233]
Corresponding Author of This Article
Georgios Tsoulfas, MD, PhD, 1st Department of Surgery, Aristotle University of Thessaloniki, 66 Tsimiski Street, Thessaloniki 54453, Greece. tsoulfasg@auth.gr
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Dec 27, 2017; 9(12): 233-245 Published online Dec 27, 2017. doi: 10.4240/wjgs.v9.i12.233
Advances and challenges in laparoscopic surgery in the management of hepatocellular carcinoma
Ioannis A Ziogas, Georgios Tsoulfas
Ioannis A Ziogas, Medical School, Aristotle University of Thessaloniki, Thessaloniki 54453, Greece
Georgios Tsoulfas, Associate Professor of Surgery, 1st Department of Surgery, Aristotle University of Thessaloniki, Thessaloniki 54453, Greece
Author contributions: Ziogas IA and Tsoulfas G contributed to all aspects of this work.
Conflict-of-interest statement: The authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Georgios Tsoulfas, MD, PhD, 1st Department of Surgery, Aristotle University of Thessaloniki, 66 Tsimiski Street, Thessaloniki 54453, Greece. tsoulfasg@auth.gr
Telephone: +30-69-71895190 Fax: +30-23-10332022
Received: September 19, 2017 Peer-review started: September 21, 2017 First decision: October 31, 2017 Revised: November 4, 2017 Accepted: December 5, 2017 Article in press: December 5, 2017 Published online: December 27, 2017 Processing time: 98 Days and 7.3 Hours
Core Tip
Core tip: Hepatocellular carcinoma is the most common primary malignant tumor of the liver and fifth most common malignancy worldwide. Surgical resection is the therapeutic treatment of choice and its laparoscopic version has come into play since 1992. Several matched comparative studies reported its superiority over open resection regarding operating theatre time and hospital stay, blood loss, need for transfusion and postsurgical opioid analgesics, postoperative pain, morbidity, R0 resection, time to recuperation, time to oral intake and stress response. The high costs of the procedure are offset by the decrease in the length of the operation and hospital stay, while in experienced hands conversion rates and morbidity are even more diminished. Laparoscopic and robotic liver resection is a continuously evolving field of minimally invasive liver surgery with a very promising future.
