Sofo L, Caprino P, Sacchetti F, Bossola M. Restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis: A narrative review. World J Gastrointest Surg 2016; 8(8): 556-563 [PMID: 27648159 DOI: 10.4240/wjgs.v8.i8.556]
Corresponding Author of This Article
Maurizio Bossola, MD, Division of General Surgery, Catholic University of the Sacred Heart, Largo A. Gemelli, 8, 00168 Rome, Italy. maubosso@tin.it
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Aug 27, 2016; 8(8): 556-563 Published online Aug 27, 2016. doi: 10.4240/wjgs.v8.i8.556
Restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis: A narrative review
Luigi Sofo, Paola Caprino, Franco Sacchetti, Maurizio Bossola
Luigi Sofo, Paola Caprino, Maurizio Bossola, Division of General Surgery, Catholic University of the Sacred Heart, 00168 Rome, Italy
Franco Sacchetti, Division of Gastroenterology, Catholic University of the Sacred Heart, 00168 Rome, Italy
Author contributions: All of the authors have made substantial contributions to the conception and design of the study, data acquisition, or data analysis and interpretation, drafting of the article or critically revising it for important intellectual content, final approval of the version to be submitted.
Conflict-of-interest statement: The authors declare no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Maurizio Bossola, MD, Division of General Surgery, Catholic University of the Sacred Heart, Largo A. Gemelli, 8, 00168 Rome, Italy. maubosso@tin.it
Telephone: +39-6-30155485 Fax: +39-6-30155491
Received: February 20, 2016 Peer-review started: February 24, 2016 First decision: March 23, 2016 Revised: April 9, 2016 Accepted: May 17, 2016 Article in press: May 27, 2016 Published online: August 27, 2016
Core Tip
Core tip: Restorative proctocolectomy with ileal pouch-anal anastomosis (RP-IPAA) is the preferred surgical treatment for ulcerative colitis. However, despite the widespread use of RP-IPAA, many aspects of this treatment still remain controversial, such as the approach (open or laparoscopic), number of stages of surgery, type of pouch, and type of construction (e.g., hand-sewn or stapled ileal pouch-anal anastomosis). Few large, randomized, controlled studies have been conducted, which limits the conclusions that can be drawn regarding controversial issues associated with RP-IPAA. It is suggested that prospective, randomized studies should be conducted in the future to compare the frequency of post-operative complications, cosmetic results, short- and long-term functional outcomes, and quality of life associated with the available techniques of RT-IPAA for the treatment of ulcerative colitis.
