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Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Feb 27, 2016; 8(2): 124-133
Published online Feb 27, 2016. doi: 10.4240/wjgs.v8.i2.124
Associating liver partition and portal vein ligation for staged hepatectomy: From technical evolution to oncological benefit
Jun Li, Florian Ewald, Amit Gulati, Björn Nashan
Jun Li, Florian Ewald, Björn Nashan, Department of Hepatobiliary and Transplant Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany
Amit Gulati, Department of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany
Author contributions: Li J design of the study, literature review and analysis, drafted and wrote the final version of the manuscript; Ewald F literature review, drafted and wrote the final version of the manuscript; Gulati A literature review, drafted and wrote the final version of the manuscript; Nashan B design of the study, critical revision, edited and final approval of the final version
Conflict-of-interest statement: The authors declare no conflicts of interest regarding this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jun Li, MD, Department of Hepatobiliary and Transplant Surgery, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany. j.li@uke.de
Telephone: +49-40-741058572 Fax: +49-40-741045001
Received: August 7, 2015
Peer-review started: August 10, 2015
First decision: September 18, 2015
Revised: October 8, 2015
Accepted: December 9, 2015
Article in press: December 11, 2015
Published online: February 27, 2016
Processing time: 205 Days and 1.4 Hours
Core Tip

Core tip: We provide a comprehensive overview of the technical evolution of Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) with a special emphasis on safety and oncologic efficacy. Furthermore, we review the contemporary literature regarding indication and benefits, but also limitations of ALPPS.