Retrospective Cohort Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Oct 27, 2016; 8(10): 693-699
Published online Oct 27, 2016. doi: 10.4240/wjgs.v8.i10.693
Acute appendicitis: Epidemiology, treatment and outcomes- analysis of 16544 consecutive cases
Marco Ceresoli, Alberto Zucchi, Niccolò Allievi, Asaf Harbi, Michele Pisano, Giulia Montori, Arianna Heyer, Gabriela E Nita, Luca Ansaloni, Federico Coccolini
Marco Ceresoli, Niccolò Allievi, Asaf Harbi, Michele Pisano, Giulia Montori, Gabriela E Nita, Luca Ansaloni, Federico Coccolini, General Surgery Unit, Papa Giovanni XXIII Hospital, 24127 Bergamo, Italy
Alberto Zucchi, Epidemiology unit, ATS Provincia Bergamo, 24128 Bergamo, Italy
Arianna Heyer, University of California, Berkeley, CA 94720, United States
Author contributions: Ceresoli M, Zucchi A, Pisano M, Ansaloni L and Coccolini F designed the study; Ceresoli M, Zucchi A, Allievi N and Pisano M analyzed the data; Ceresoli M, Allievi N, Harbi A and Montori G wrote the paper; Pisano M, Heyer A, Nita GE, Ansaloni L and Coccolini F revised it critically; all the authors read and approved the final version of the manuscript.
Institutional review board statement: According to the Italian law for retrospective observational cohort studies no specific approvations by the review board is needed.
Informed consent statement: This is a retrospective cohort study. According to the Italian law and the Helsinki declaration on biohetics no informed consent by single patient is needed; moreover presented data are anonymized and risk of identification is null.
Conflict-of-interest statement: No potential conflicts of interest relevant to this article were reported.
Data sharing statement: Statistical code and dataset are available from the corresponding author at marco.ceresoli@libero.it. Consent was not obtained but the presented data are anonymized and risk of identification is null. No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Marco Ceresoli, General Surgery Unit, Papa Giovanni XXIII Hospital, piazza OMS 1, 24127 Bergamo, Italy. marco.ceresoli@libero.it
Telephone: +39-352-673486 Fax: +39-352-674963
Received: May 31, 2016
Peer-review started: June 1, 2016
First decision: July 20, 2016
Revised: August 4, 2016
Accepted: August 27, 2016
Article in press: August 29, 2016
Published online: October 27, 2016
Processing time: 146 Days and 20.9 Hours
Core Tip

Core tip: Acute appendicitis is the most common surgical emergency around the world. In the Bergamo district, northern Italy its incidence is 89/100000 inhabitants per year with a negative trend during the last years. Percent of 95 patients were treated with appendectomy, 48% of whom laparoscopically; 1.3% of operated patients had an intestinal obstruction during the follow-up. Conservative treatment resulted in a reduced length of stay but 23% of patients had a relapse during follow up. Cumulative length of stays during the study period was similar for the two treatment option.