Tumor differentiation as related to sentinel lymph node status in gastric cancer

doi:10.4240/wjgs.v6.i1.1

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Jan 27, 2014 (publication date) through Apr 25, 2024

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Jan 27, 2014; 6(1): 1-4
Published online Jan 27, 2014. doi: 10.4240/wjgs.v6.i1.1

Tumor differentiation as related to sentinel lymph node status in gastric cancer

Ron Lavy, Andronik Kapiev, Yehuda Hershkovitz, Natan Poluksht, Igor Rabin, Bar Chikman, Zahar Shapira, Ilan Wasserman, Judith Sandbank, Ariel Halevy

Ron Lavy, Andronik Kapiev, Yehuda Hershkovitz, Natan Poluksht, Igor Rabin, Bar Chikman, Zahar Shapira, Ilan Wasserman, Ariel Halevy, Division of Surgery, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Zerifin 70300, Israel

Igor Rabin, Department of Vascular Surgery, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Zerifin 70300, Israel

Judith Sandbank, Institute of Pathology, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Zerifin 70300, Israel

Author contributions: Lavy R, Kapiev A and Halevy A conceived and designed the study; Lavy R, Hershkovitz Y, Sandbank J and Halevy A analyzed and interpreted the data; Halevy A performed critical revision of the article for important intellectual content; all authors acquired the data, wrote the draft of the article and gave final approval of the version to be published.

Correspondence to: Ariel Halevy, Professor, Division of Surgery, Assaf Harofeh Medical Center, Tel-Aviv University, Weizmann 10, Ramat Aviv, Zerifin 70300, Israel. fredricag@asaf.health.gov.il

Telephone: +972-8-9779222 Fax: +972-8-9779225

Received: August 28, 2013
Revised: December 11, 2013
Accepted: December 17, 2013
Published online: January 27, 2014

Core Tip

Core tip: The application of sentinel lymph node (SLN) sampling in gastric cancer is limited to the early stages of the disease. The results of the sampling, which is usually not one node but rather a group of nodes, might influence the extent of lymphadenectomy to be performed. In a previous study, we clearly showed that the accuracy of SLN testing is inversely proportionate to the T stage of the tumor. In this retrospective study, we evaluated the level of tumor differentiation as related to the SLN status. Our study showed that there was no correlation between tumor differentiation and SLN status.