Brief Article
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World J Gastrointest Surg. Jun 27, 2013; 5(6): 178-186
Published online Jun 27, 2013. doi: 10.4240/wjgs.v5.i6.178
Impact of medical and surgical intervention on survival in patients with cholangiocarcinoma
Amanda K Arrington, Rebecca A Nelson, Ann Falor, Carrie Luu, Rebecca L Wiatrek, Marwan Fakih, Gagandeep Singh, Joseph Kim
Amanda K Arrington, Rebecca L Wiatrek, Gagandeep Singh, Joseph Kim, Division of Surgical Oncology, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, United States
Rebecca A Nelson, Department of Biostatistics, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, United States
Ann Falor, Carrie Luu, Department of Surgery, Harbor-UCLA Medical Center, Torrance, CA 90509, United States
Marwan Fakih, Department of Medical Oncology, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, United States
Author contributions: Arrington AK, Nelson RA, Wiatrek RL and Kim J designed and performed the research; Nelson RA contributed new analytic tools; Arrington AK, Nelson RA, Kim J analyzed data; Arrington AK, Nelson RA, Falor A, Luu C, Wiatrek RL, Fakih M, Singh G and Kim J wrote the paper.
Correspondence to: Joseph Kim, MD, Division of Surgical Oncology, City of Hope Comprehensive Cancer Center, 1500 East Duarte Road, Duarte, CA 91010, United States. jokim@coh.org
Telephone: +1-626-4717100 Fax: +1-626-3018865
Received: February 25, 2013
Revised: April 16, 2013
Accepted: May 8, 2013
Published online: June 27, 2013
Processing time: 119 Days and 3.9 Hours
Core Tip

Core tip: Cholangiocarcinoma is an aggressive biliary tract cancer with few treatment options. Surgical resection has been the only available curative-intent treatment in early disease. This study demonstrates that multimodality therapy may provide the best improvement in survival.