Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Apr 27, 2025; 17(4): 105096
Published online Apr 27, 2025. doi: 10.4240/wjgs.v17.i4.105096
Laparoscopic management of intraductal oncocytic papillary neoplasm of the pancreas: Two case reports and review of literature
Guo-Zhen Wu, Li-Na Lu, Hai-Ping Lin, Xin-Yu Wang, Shi-An Yu, Min Yu
Guo-Zhen Wu, Hai-Ping Lin, Shi-An Yu, Min Yu, Department of Hepatobiliary and Pancreatic Surgery, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua 321000, Zhejiang Province, China
Li-Na Lu, Department of Gastroenterology, Wenrong Hospital of Jinhua City, Jinhua 321000, Zhejiang Province, China
Xin-Yu Wang, Department of Radiology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua 321000, Zhejiang Province, China
Co-first authors: Guo-Zhen Wu and Li-Na Lu.
Author contributions: Wu GZ wrote the manuscript; Lu LN participated in data collection; Lin HP and Wang XY helped revise the manuscript; Yu SA and Yu M designed the study; Wu GZ and Lu LN contributed equally to this work; All authors have read and approved the final manuscript.
Supported by the Zhejiang Medical Science and Technology Project, No. 2022KY1325 and No. 2023KY381.
Informed consent statement: Informed written consent were obtained from the patients for publication of these case reports and accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Min Yu, MD, Chief Physician, Professor, Department of Hepatobiliary and Pancreatic Surgery, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, No. 365 Renmin East Road, Wucheng District, Jinhua 321000, Zhejiang Province, China. greendoctor@163.com
Received: January 13, 2025
Revised: February 4, 2025
Accepted: March 3, 2025
Published online: April 27, 2025
Processing time: 76 Days and 4.2 Hours
Core Tip

Core Tip: Intraductal oncocytic papillary neoplasm (IOPN) of the pancreas is extremely rare. The mechanism of the disease is not fully understood. Here, we reported 2 cases of pancreatic IOPN that were treated with laparoscopic surgery, covering its clinical manifestations, imaging findings, pathological morphological and immunophenotype, clinical treatment and prognosis, aiming to provide references for clinicians and improve the level of diagnosis and treatment of similar cases. Since a certain proportion of cases may be associated with invasive cancer, surgery is the preferred treatment. Laparoscopic surgery can be considered as one of the treatment options for IOPN of the pancreas.