Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Apr 27, 2025; 17(4): 102730
Published online Apr 27, 2025. doi: 10.4240/wjgs.v17.i4.102730
Gastric adenocarcinoma of fundic gland mucosa arising in heterotopic gastric mucosa of the duodenum: A case report
Qun-Ying Yang, Jing Xu, Jian-Wen Hu, Xiao-Dong Huang
Qun-Ying Yang, Jian-Wen Hu, Department of Gastroenterology, Dongyang People’s Hospital, Dongyang 322100, Zhejiang Province, China
Jing Xu, Department of Pathology, Affiliated Sir Run Run Shaw Hospital of Zhejiang University School of Medicine, Hangzhou 310000, Zhejiang Province, China
Xiao-Dong Huang, Department of Gastroenterology, Yiwu Tianxiang Medical East Hospital, Yiwu 322000, Zhejiang Province, China
Author contributions: Yang QY and Huang XD cared for the patient; Yang QY and Xu J were involved doing a literature search and wrote the paper; Hu JW and Huang XD reviewed the manuscript and submitted the paper. All authors read and approved the final version.
Informed consent statement: Written informed consent was obtained from the patient for the publication of this case report and any accompanying images. All identifying details have been removed or anonymized to protect the patient’s privacy.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Dong Huang, MD, Professor, Chief Physician, Department of Gastroenterology, Yiwu Tianxiang Medical East Hospital, No. 188 Nanshan Road, Yiwu 322000, Zhejiang Province, China. xiaodonghuang2024@163.com
Received: October 28, 2024
Revised: December 16, 2024
Accepted: February 11, 2025
Published online: April 27, 2025
Processing time: 152 Days and 19.5 Hours
Core Tip

Core Tip: This case represents the first reported of gastric adenocarcinoma of fundic gland mucosa in the duodenum arising from heterotopic gastric mucosa. The article highlights a rare occurrence, which could be of great interest to medical professionals encountering similar cases. The collaboration between the gastroenterology and pathology departments in different hospitals shows the importance of interdisciplinary teamwork in diagnosing and treating complex medical cases.