Lou QX, Xu KP. Analgesic effect and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive inguinal hernia surgery. World J Gastrointest Surg 2025; 17(3): 99597 [DOI: 10.4240/wjgs.v17.i3.99597]
Corresponding Author of This Article
Ke-Ping Xu, Department of Anesthesia, Zhuji Traditional Chinese Medicine Hospital of Zhejiang Province, No. 521 East 2nd Road, Huandong Street, Shaoxing 311800, Zhejiang Province, China. xkp18767533987@163.com
Research Domain of This Article
Anesthesiology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Mar 27, 2025; 17(3): 99597 Published online Mar 27, 2025. doi: 10.4240/wjgs.v17.i3.99597
Analgesic effect and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive inguinal hernia surgery
Qian-Xing Lou, Ke-Ping Xu
Qian-Xing Lou, Department of Anesthesiology, Yiwu Central Hospital, Yiwu 322000, Zhejiang Province, China
Ke-Ping Xu, Department of Anesthesia, Zhuji Traditional Chinese Medicine Hospital of Zhejiang Province, Shaoxing 311800, Zhejiang Province, China
Author contributions: Lou QX and Xu KP contributed to conception, design, data analysis, and manuscript drafting and editing; Lou QX and Xu KP contributed to collection, assembly of data and revised the manuscript; Lou QX and Xu KP contributed to conception, resources, and manuscript review and editing; all authors have read and approved the final manuscript.
Institutional review board statement: This study was approved by the Ethic Committee of Yiwu Central Hospital.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement:sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ke-Ping Xu, Department of Anesthesia, Zhuji Traditional Chinese Medicine Hospital of Zhejiang Province, No. 521 East 2nd Road, Huandong Street, Shaoxing 311800, Zhejiang Province, China. xkp18767533987@163.com
Received: November 21, 2024 Revised: January 2, 2025 Accepted: January 20, 2025 Published online: March 27, 2025 Processing time: 94 Days and 18.8 Hours
Core Tip
Core Tip: This study aimed to assess the analgesic effect and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for inguinal hernia through systematic clinical observation and analysis. The study enrolled a total of 94 patients with inguinal hernia who were scheduled to undergo laparoscopic minimally invasive surgery. Comparative analyses were performed on the clinical outcomes between inhalation anesthesia combined with general anesthesia and dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in these patients. The results revealed that dexmedetomidine-assisted intravenous-inhalation combined general anesthesia can facilitate the early recovery of patients undergoing laparoscopic minimally invasive surgery for inguinal hernia, ensure hemodynamic stability, enhance postoperative analgesic effects, alleviate stress response, and improve immune function while exhibiting a certain safety level.
