Retrospective Cohort Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Mar 27, 2025; 17(3): 94286
Published online Mar 27, 2025. doi: 10.4240/wjgs.v17.i3.94286
Efficacy of fluorouracil combined with paclitaxel and oxaliplatin for the treatment of advanced gastric signet ring cell carcinoma
Mi Liu, Bei Feng, Na He, Rong Yan, Jie Qin
Mi Liu, Department of Gastroenterology, The First Affiliated Hospital of Xi’an Medical University, Xi’an 710077, Shaanxi Province, China
Bei Feng, Department of Oncology, The Affiliated Hospital of Yan’an University, Yan’an 716000, Shaanxi Province, China
Na He, Rong Yan, Jie Qin, Department of Gastroenterology, The First Affiliated Hospital of Xi'an Medical University, Xi'an 710077, Shaanxi Province, China
Author contributions: Qin J designed the study; Liu M wrote the original draft; Feng B, He N, and Yan R collected the raw data; Yan R performed the statistical and bioinformatics analyses; Qin J supervised the study; All authors have read and approved the final version of the manuscript.
Institutional review board statement: The Ethics Committee of the First Affiliated Hospital of Xi'an Medical University approved the study, No. XYYFYLL-KTSB-2024-10.
Informed consent statement: All patients obtained written informed consent.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Data sharing statement: The data used to support this study are available from the corresponding author upon request at qinjie202202@163.com.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work Non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is Non-Commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jie Qin, Department of Gastroenterology, The First Affiliated Hospital of Xi'an Medical University, No. 48 Fenghao West Road, Lianhu District, Xi'an 710077, Shaanxi Province, China. qinjie202202@163.com
Received: March 14, 2024
Revised: September 17, 2024
Accepted: December 25, 2024
Published online: March 27, 2025
Processing time: 346 Days and 14 Hours
Core Tip

Core Tip: This study explored the clinical efficacy of fluorouracil combined with paclitaxel and oxaliplatin for the treatment of patients with advanced gastric signet ring cell carcinoma, and analyzed the role of serum carcinoembryonic antigen, carbohydrate antigen 19-9, albumin, and total protein levels in evaluating chemotherapy efficacy.