Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Mar 27, 2025; 17(3): 102190
Published online Mar 27, 2025. doi: 10.4240/wjgs.v17.i3.102190
Analysis of risk factors for bile leakage after laparoscopic exploration and primary suture of common bile duct
Qing-Song Yang, Meng Zhang, Chang-Song Ma, Da Teng, Ao Li, Ji-Dong Dong, Xi-Fei Wang, Fu-Bao Liu
Qing-Song Yang, Meng Zhang, Chang-Song Ma, Da Teng, Ao Li, Ji-Dong Dong, Xi-Fei Wang, Department of Hepatopancreatobiliary Surgery, Affiliated Chuzhou Hospital of Anhui Medical University (The First People’s Hospital of Chuzhou), Chuzhou 239001, Anhui Province, China
Fu-Bao Liu, Department of Hepatobiliary and Pancreatic Surgery, General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China
Author contributions: Yang QS contributed to the study design and data analysis; Zhang M, Ma CS, Teng D, Li A, Dong JD, and Wang XF assisted with data collection and interpretation; Liu FB provided critical revisions and clinical insights, supervised the research and served as the corresponding author; and all authors thoroughly reviewed and endorsed the final manuscript.
Supported by the Wannan Medical College Teaching Hospital Special Application for Scientific Research, No. WK2023JXYY036; and the Anhui Provincial Translational Clinical Medical Research Special Application, No. 202204295107020062.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the First People’s Hospital of Chuzhou, approval No. (2024) Ethics Review [Biology] (29).
Informed consent statement: Informed consent was obtained from all participants, and the study was approved by Wannan Medical College.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The data used in this study can be obtained from the corresponding author upon reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fu-Bao Liu, Chief Physician, PhD, Department of Hepatobiliary and Pancreatic Surgery, General Surgery, The First Affiliated Hospital of Anhui Medical University, No. 120 Wanshui Road, Nanqiao District, Hefei 230022, Anhui Province, China. 18955015210@163.com
Received: October 23, 2024
Revised: December 23, 2024
Accepted: January 8, 2025
Published online: March 27, 2025
Processing time: 123 Days and 23.7 Hours
Core Tip

Core Tip: This study identifies key risk factors for bile leakage following laparoscopic common bile duct exploration and primary duct closure (PDC). Through retrospective analysis and logistic regression, fibrinous exudation and direct bilirubin/indirect bilirubin were found to be significant independent risk factors. The cumulative summation method demonstrated that a minimum of 51 cases is required for surgeons to master the PDC technique effectively. Proper assessment of duodenal papilla function, ensuring bile duct patency, and achieving surgical proficiency are essential for minimizing complications. Adhering to these guidelines may optimize patient outcomes and promote PDC as a preferred method in clinical practice.