Retrospective Study
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World J Gastrointest Surg. Mar 27, 2025; 17(3): 101786
Published online Mar 27, 2025. doi: 10.4240/wjgs.v17.i3.101786
Efficacy of microwave ablation vs laparoscopic hepatectomy for primary small liver cancer: A comparative study
Huan-Song Li, Xuan-Feng Zhang, Jun Fu, Bo Yuan
Huan-Song Li, Xuan-Feng Zhang, Jun Fu, Bo Yuan, Department of Hepatobiliary Pancreatic Center, Xuzhou Central Hospital, Xuzhou 221009, Jiangsu Province, China
Co-first authors: Huan-Song Li and Xuan-Feng Zhang.
Co-corresponding authors: Jun Fu and Bo Yuan.
Author contributions: Li HS and Zhang XF designed the research and wrote the first manuscript; Li HS, Zhang XF, Fu J and Yuan B contributed to conceiving the research and analyzing data, conducted the analysis and provided guidance for the research; all authors reviewed and approved the final manuscript. Li HS and Zhang XF contributed equally to this work as co-first authors. Both Fu J and Yuan B have played important and indispensable roles in the experimental design, data interpretation and manuscript preparation as the co-corresponding authors. Yuan B conceptualized, designed, and supervised the whole process of the project. Fu J searched the literature, revised and submitted the early version of the manuscript. Fu J and Yuan B was instrumental and responsible for data re-analysis and re-interpretation, figure plotting, comprehensive literature search, preparation and submission of the current version of the manuscript. This collaboration between Fu J and Yuan B is crucial for the publication of this manuscript and other manuscripts still in preparation.
Institutional review board statement: This study was approved by the Ethic Committee of Xuzhou Central Hospital.
Informed consent statement: The requirement for written informed consent was waived due to retrospective design of the study.
Conflict-of-interest statement: The authors declare no conflict of interest.
Data sharing statement: The statistical data used in this study can be obtained from the corresponding author upon request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bo Yuan, Associate Chief Physician, Department of Hepatobiliary Pancreatic Center, Xuzhou Central Hospital, No. 199 Jiefang South Road, Quanshan District, Xuzhou 221009, Jiangsu Province, China. shimingyb666@sina.com
Received: November 7, 2024
Revised: December 13, 2024
Accepted: January 7, 2025
Published online: March 27, 2025
Processing time: 108 Days and 19.5 Hours
Core Tip

Core Tip: This study primarily aimed to comparatively analyze the clinical effectiveness of liver tumor microwave ablation (MWA) and laparoscopic hepatectomy (LH) in treating primary small liver cancer (PSLC). We conducted a comparative analysis of the two intervention methods from multiple perspectives, including various perioperative indicators, changes in liver function indicators pre- and post-treatment, curative effects, and postoperative complications. This study confirmed that MWA demonstrated better curative effects than LH in PSLC treatment, with a reduced intraoperative blood loss level, shorter surgical procedure and hospitalization durations, rapid recovery facilitation, liver function improvement, postoperative complication reduction, and a high safety level. Therefore, selecting the appropriate surgical method is the key to achieving better clinical outcomes. Our analysis provides more reliable clinical references and options for future PSLC treatment.