Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Feb 27, 2025; 17(2): 100631
Published online Feb 27, 2025. doi: 10.4240/wjgs.v17.i2.100631
Preliminary study on the clinical value of endoscopic stricturotomy in the treatment of stricturing Crohn's disease
Lu Cui, Min Su, Yan-Bo Ding, Mei Wang, Ke-Wen Sun
Lu Cui, Min Su, Yan-Bo Ding, Mei Wang, Ke-Wen Sun, Department of Gastroenterology, The Third Affiliated Hospital of Soochow University, Changzhou 213000, Jiangsu Province, China
Co-corresponding authors: Mei Wang and Ke-Wen Sun.
Author contributions: All authors participated in the conception and design of the study; Cui L, Su M, Ding YB, Wang M and Sun KW devised the research; Wang M executed the endoscopic stricturotomy; Cui Land Su M screened patients and acquired clinical data; Ding YB performed data analysis; Sun KW carried out supervision and validation; Cui L drafted the initial manuscript; All authors provided comments on previous versions. Both Wang M and Sun KW have played important and indispensable roles in the experimental design, data interpretation and manuscript preparation as the co-corresponding authors. Wang M performed endoscopic operations. She consulted the literature and revised the early version of the manuscript. Sun KW conceived, designed, and supervised the entire process of the project. He combined the analyzed data with national and international studies to further explain the utility of endoscopic stricturotomy. The collaboration between Wang M and Sun KW was crucial to the publication of the manuscript.
Institutional review board statement: The study was retrospective and has been approved by the Ethics Committee of The First People’s Hospital of Changzhou (2024 Section 180).
Informed consent statement: The study was a retrospective study. The data were anonymous, and the requirement for informed consent was therefore waived.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The data that support the findings of this study are available from the corresponding author upon reasonable request at maywang2007@hotmail.com.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mei Wang, Chief Physician, Department of Gastroenterology, The Third Affiliated Hospital of Soochow University, No. 185 Juqian Street, Changzhou 213000, Jiangsu Province, China. maywang2007@hotmail.com
Received: August 22, 2024
Revised: November 22, 2024
Accepted: December 17, 2024
Published online: February 27, 2025
Processing time: 153 Days and 19.3 Hours
Core Tip

Core Tip: This study evaluated the efficacy and safety of endoscopic stricturotomy (ES) for treating stricturing Crohn's disease in 11 patients. ES achieved a 100% immediate success rate with no significant complications. During follow-up, symptom relief was maintained for a median of 10 months, and the need for surgical intervention was reduced. ES was particularly effective for short-segment, solitary strictures and provided precise, minimally invasive treatment. These findings suggest ES is a viable alternative to surgery, which improves patient outcomes and delays recurrence or progression. Further research with larger sample sizes and multicenter studies is needed to validate these results.