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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Sep 27, 2024; 16(9): 2942-2952
Published online Sep 27, 2024. doi: 10.4240/wjgs.v16.i9.2942
Published online Sep 27, 2024. doi: 10.4240/wjgs.v16.i9.2942
Advancing gastrointestinal stromal tumor management: The role of imagomics features in precision risk assessment
Gui-Hai Pan, Wu-Biao Chen, Ze-Jun Pan, Department of Radiology, The Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, Guangdong Province, China
Fei Zhou, Department of Endocrinology, The Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, Guangdong Province, China
Author contributions: Pan GH and Zhou F conceived and designed the study; Chen WB, Pan ZJ, and Zhou F performed the experiments; Pan GH and Chen WB analyzed the data; Pan ZJ and Zhou F wrote the manuscript. All authors reviewed and approved the final version of the manuscript.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of the Affiliated Hospital of Guangdong Medical University.
Informed consent statement: All participants or their legal representatives voluntarily signed written informed consent forms.
Conflict-of-interest statement: The author declares no conflict of interest.
Data sharing statement: All data can be provided as needed.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fei Zhou, Department of Endocrinology, The Affiliated Hospital of Guangdong Medical University, No. 57 Renmin Avenue South, Xiashan District, Zhanjiang 524001, Guangdong Province, China. 022141130@mails.ccu.edu.cn
Received: March 25, 2024
Revised: May 24, 2024
Accepted: July 17, 2024
Published online: September 27, 2024
Processing time: 176 Days and 11.9 Hours
Revised: May 24, 2024
Accepted: July 17, 2024
Published online: September 27, 2024
Processing time: 176 Days and 11.9 Hours
Core Tip
Core Tip: This study unveils the transformative potential of magnetic resonance imaging (MRI) imagomics in the preoperative risk stratification of gastrointestinal stromal tumors (GISTs), challenging traditional, pathology-based assessments. By analyzing imagomics features from MRI sequences, particularly diffusion-weighted imaging and a combined T1-weighted imaging (T1WI)/contrast enhanced T1WI with fat saturation fat suppress model, we have demonstrated unprecedented accuracy in predicting GIST risk levels. These findings not only enhance the precision of preoperative evaluations but also pave the way for more personalized treatment plans, aligning closely with the goals of precision medicine in oncology.