Retrospective Cohort Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Sep 27, 2024; 16(9): 2778-2786
Published online Sep 27, 2024. doi: 10.4240/wjgs.v16.i9.2778
Transjugular intrahepatic portosystemic shunt for esophagogastric variceal bleeding in patients with hepatocellular carcinoma and portal vein tumor thrombus
Zhi-Qiang Wu, Fan Wang, Feng-Pin Wang, Hong-Jie Cai, Song Chen, Jian-Yong Yang, Wen-Bo Guo
Zhi-Qiang Wu, Fan Wang, Hong-Jie Cai, Song Chen, Jian-Yong Yang, Wen-Bo Guo, Department of Interventional Radiology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China
Feng-Pin Wang, Department of Medical Oncology, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 510080, Guangdong Province, China
Author contributions: Wu ZQ and Wang F contributed equally to this work. Wu ZQ, Wang F, and Guo WB were involved in the study design, data collection, analysis and interpretation of data, data quality control and validation and study supervision; Wu ZQ and Wang F were involved in the drafting of the manuscript; Wang FP, Cai HJ, Chen S, and Yang JY were involved in the data quality control and validation, critical revision of the manuscript for important intellectual content.
Institutional review board statement: The study was approved by the Ethics Committee of the First Affiliated Hospital of Sun Yat-sen University (Approval No: [2022]120).
Informed consent statement: The requirement for informed consent was waived by the committee due to the retrospective study nature of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The original anonymous dataset is available on request from the corresponding author.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wen-Bo Guo, PhD, Department of Interventional Radiology, The First Affiliated Hospital of Sun Yat-sen University, No. 58 Zhongshaner Road, Guangzhou 510080, Guangdong Province, China. guowenbo@mail.sysu.edu.cn
Received: March 6, 2024
Revised: May 30, 2024
Accepted: August 1, 2024
Published online: September 27, 2024
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Core Tip

Core Tip: This study compared the clinical outcomes between transjugular intrahepatic portosystemic shunt (TIPS) treatment and standard conservative treatment in hepatocellular carcinoma patients with portal vein tumor thrombus and acute esophagogastric variceal bleeding. And showed that TIPS could reduce the risk of rebleeding by decreasing portal pressure, leading to prolonged short-term survival in hepatocellular carcinoma patients with portal vein tumor thrombus and acute esophagogastric variceal bleeding compared with standard conservative treatment. The safety of TIPS was also acceptable.