Randomized Clinical Trial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Aug 27, 2024; 16(8): 2671-2678
Published online Aug 27, 2024. doi: 10.4240/wjgs.v16.i8.2671
Application value of dexmedetomidine in anesthesia for elderly patients undergoing radical colon cancer surgery
Hui-Min Bu, Min Zhao, Hong-Mei Ma, Xiao-Peng Tian
Hui-Min Bu, Min Zhao, Hong-Mei Ma, Xiao-Peng Tian, Department of Anesthetic Surgery, Qingdao Haici Hospital Affiliated to Qingdao University (Qingdao Hospital of Traditional Chinese Medicine), Qingdao 266033, Shandong Province, China
Author contributions: Bu HM and Tian XP designed the research; Bu HM and Zhao M performed the research; Bu HM and Ma HM analyzed the data; Bu HM and Tian XP wrote the manuscript.
Institutional review board statement: This study was approved by the institutional review board of Qingdao Haici Hospital Affiliated to Qingdao University (No. 2020).
Clinical trial registration statement: As the authors' institution and ethics committee did not require clinical trial registration prior to the study, this study was not registered.
Informed consent statement: Informed consent was obtained from every participant.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The data are available from the corresponding author at txp21359079@163.com.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Xiao-Peng Tian, MA, Attending Doctor, Department of Anesthetic Surgery, Qingdao Haici Hospital Affiliated to Qingdao University (Qingdao Hospital of Traditional Chinese Medicine), No. 4 Renmin Road, Shibei District, Qingdao 266033, Shandong Province, China. txp21359079@163.com
Received: March 12, 2024
Revised: June 8, 2024
Accepted: July 8, 2024
Published online: August 27, 2024
Processing time: 157 Days and 10.3 Hours
Core Tip

Core Tip: This study aimed to explore the impact of dexmedetomidine (Dex) as an adjunct to general anesthesia on bispectral index, cognitive function, and local brain oxygen saturation in elderly patients undergoing radical colon cancer surgery. The use of Dex as an adjunct to general anesthesia in elderly patients undergoing radical colon cancer surgery helps maintain regional cerebral oxygen saturation levels and reduce cerebral metabolic levels, thereby lowering the incidence of anesthesia- and surgery-induced cognitive dysfunction and reducing the dosage of related anesthetic drugs.