Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Aug 27, 2024; 16(8): 2565-2573
Published online Aug 27, 2024. doi: 10.4240/wjgs.v16.i8.2565
Systemic immune-inflammation index combined with pediatric appendicitis score in assessing the severity and prognosis for paediatric appendicitis
Li-Ming Guo, Zhi-Hui Jiang, Hong-Zhen Liu
Li-Ming Guo, Zhi-Hui Jiang, Department of General Surgery, Qingdao Women and Children’s Hospital, Qingdao 266000, Shandong Province, China
Hong-Zhen Liu, Department of Pediatric Surgery, Children's Hospital Affiliated to Shandong University, Jinan 250022, Shandong Province, China
Hong-Zhen Liu, Department of Pediatric Surgery, Jinan Children's Hospital, Jinan 250022, Shandong Province, China
Co-first authors: Li-Ming Guo and Zhi-Hui Jiang.
Author contributions: Guo LM and Jiang ZH are co-first authors and contributed equally to this work, including design of the study, acquiring and analyzing data from experiments, and writing of the manuscript; Guo LM, Jiang ZH and Liu HZ designed the experiments and conducted clinical data collection; Guo LM and Jiang ZH performed postoperative follow-up and recorded the data, conducted the collation and statistical analysis, and wrote the original manuscript and revised the paper; all authors read and approved the final manuscript.
Institutional review board statement: This study was approved by the Ethics Committee of Qingdao Women and Children’s Hospital.
Informed consent statement: The Ethics Committee has agreed to waive informed consent.
Conflict-of-interest statement: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Data sharing statement: All data generated or analyzed during this study are included in this published article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li-Ming Guo, MM, Department of General Surgery, Qingdao Women and Children’s Hospital, No. 6 Tongfu Road, Shibei District, Qingdao 266000, Shandong Province, China. guolimingqdfe@163.com
Received: May 10, 2024
Revised: July 2, 2024
Accepted: July 4, 2024
Published online: August 27, 2024
Processing time: 98 Days and 3.1 Hours
Core Tip

Core Tip: This study investigates the combined use of the Systemic Immune-inflammation index (SII) and pediatric appendicitis score (PAS) to predict disease severity and surgical outcomes in children aged 5 years and older with appendicitis. The results demonstrate significant improvements in clinical decision-making and prognosis assessment. Integrating SII and PAS provides a comprehensive assessment of the systemic inflammatory response and clinical symptoms, offering a novel and effective approach to managing pediatric appendicitis.