Copyright
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Aug 27, 2024; 16(8): 2538-2545
Published online Aug 27, 2024. doi: 10.4240/wjgs.v16.i8.2538
Published online Aug 27, 2024. doi: 10.4240/wjgs.v16.i8.2538
Indication of conservative treatment by antibiotics for uncomplicated and complicated acute appendicitis
Yuichi Hosokawa, Masato Moritani, Yosuke Makuuchi, Department of Surgery, Nishitokyo Central General Hospital, Tokyo 188-0014, Japan
Yuichi Hosokawa, Masato Moritani, Yosuke Makuuchi, Yuichi Nagakawa, Department of Gastrointestinal and Pediatric Surgery, Tokyo Medical University, Tokyo 166-0023, Japan
Author contributions: Hosokawa Y designed and performed the research and wrote the paper; Moritani M designed the research and supervised the report; Makuuchi Y designed the research and contributed to the analysis; Nagakawa Y provided clinical advice.
Institutional review board statement: Nishitokyo Central General Hospital has its own Institutional Review Board. This study was approved by the Ethics Committee of the Nishitokyo Central General Hospital, No. 2018-004.
Informed consent statement: This specific study, the ethical committee approved the lack of informed consent from the patients because of the low risk of identification due to the presented data are anonymized.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at ryu37072002@yahoo.co.jp. Participants gave informed consent for data sharing.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Yuichi Hosokawa, MD, PhD, Surgeon, Department of Surgery, Nishitokyo Central General Hospital, 2-4-19 Shibakubo-tyo, Nishitokyo-shi, Tokyo 188-0014, Japan. ryu37072002@yahoo.co.jp
Received: April 12, 2024
Revised: June 27, 2024
Accepted: June 28, 2024
Published online: August 27, 2024
Processing time: 126 Days and 12.1 Hours
Revised: June 27, 2024
Accepted: June 28, 2024
Published online: August 27, 2024
Processing time: 126 Days and 12.1 Hours
Core Tip
Core Tip: This is a retrospective study to investigate the outcomes of conservative treatment for uncomplicated and complicated acute appendicitis. The success rate of conservative treatment of acute appendicitis was 89.7%. The significant and independent predictors of resistance to conservative treatment were body temperature ≥ 37.3 °C, appendicolith and Douglas sinus fluid. The rate of resistance to conservative treatment was 66.7% for patients with the above three factors, therefore, surgical treatment should be recommended at the first visit. Body temperature ≥ 37.3 °C, appendicolith and Douglas sinus fluid might be clinical risk factors for resistance to conservative treatment for acute appendicitis.