Chen XF, Wu HJ, Li T, Liu JB, Zhou WJ, Guo Q. Establishment and validation of a predictive model for peripherally inserted central catheter-related thrombosis in patients with liver cancer. World J Gastrointest Surg 2024; 16(7): 2221-2231 [PMID: 39087116 DOI: 10.4240/wjgs.v16.i7.2221]
Corresponding Author of This Article
Qiang Guo, MD, Associate Professor, Department of Vascular Surgery, West China Hospital of Sichuan University, No. 37 Guoxue Lane, Wuhou District, Chengdu 610041, Sichuan Province, China. guoqiang6561@163.com
Research Domain of This Article
Cardiac & Cardiovascular Systems
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Xiao-Fei Chen, Jia-Bin Liu, Department of Thyroid Surgery, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China
Xiao-Fei Chen, Wen-Jie Zhou, The Second Department of General Surgery, Chengdu Shangjinnanfu Hospital, West China Hospital of Sichuan University, Chengdu 611730, Sichuan Province, China
Hao-Jun Wu, Department of Biliary Surgery, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China
Tang Li, Department of Hepatobiliary and Pancreatic Surgery, Chengdu Shangjinnanfu Hospital, West China Hospital of Sichuan University, Chengdu 611730, Sichuan Province, China
Qiang Guo, Department of Vascular Surgery, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Chen XF and Guo Q designed the experiments and conducted clinical data collection; Wu HJ, Li T, Liu JB and Zhou WJ performed postoperative follow-up and recorded the data; Chen XF and Guo Q conducted the collation and statistical analysis, wrote the original manuscript and revised the paper; All authors read and approved the final manuscript.
Institutional review board statement: This study was approved by the Ethics Committee of West China Hospital of Sichuan University (No. 2023-1712).
Informed consent statement: The Ethics Committee has agreed to waive informed consent.
Conflict-of-interest statement: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Data sharing statement: All data generated or analyzed during this study are included in this published article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qiang Guo, MD, Associate Professor, Department of Vascular Surgery, West China Hospital of Sichuan University, No. 37 Guoxue Lane, Wuhou District, Chengdu 610041, Sichuan Province, China. guoqiang6561@163.com
Received: April 30, 2024 Revised: June 3, 2024 Accepted: June 18, 2024 Published online: July 27, 2024 Processing time: 83 Days and 8.4 Hours
Core Tip
Core Tip: In this study, we comprehensively analyzed the influencing factors of peripherally inserted central catheters-related thrombosis in hospitalized patients with liver cancer. We constructed a predictive model to accurately predict the risk of thrombosis and validated its performance. Age, Karnofsky performance score, parenteral nutrition, tumor-node-metastasis staging, distant metastasis, bone marrow suppression, and activities of daily living impairment were identified as independent risk factors, while catheter duration was a protective factor. The predictive model demonstrated high accuracy, with an area under the curve of 0.827, indicating its potential clinical value in enhancing the quality of care for peripherally inserted central catheters patients with liver cancer.
