Evaluation of oxaliplatin and tigio combination therapy in locally advanced gastric cancer

doi:10.4240/wjgs.v16.i6.1709

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Jun 27, 2024 (publication date) through Jun 30, 2024

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Jun 27, 2024; 16(6): 1709-1716
Published online Jun 27, 2024. doi: 10.4240/wjgs.v16.i6.1709

Evaluation of oxaliplatin and tigio combination therapy in locally advanced gastric cancer

Teng Wang, Li-Yun Zhang

Teng Wang, Li-Yun Zhang, Department of Gastroenterology, Xianyang Hospital, Yan’an University, Xianyang 712000, Shaanxi Province, China

Author contributions: Zhang LY designed this study, collected and analyzed the data; Wang T drafted the manuscript and gave final approval of the version to be published; Wang T and Zhang LY took part in this study as endoscopic operators or assistants.

Institutional review board statement: The study was reviewed and approved by the Medical Ethics Committee of Xianyang Hospital, Yan’an University (Approval No. 2023-299).

Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.

Conflict-of-interest statement: The authors declare that there is no competing interest associated with the manuscript.

Data sharing statement: No additional data are available.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Li-Yun Zhang, MM, Associate Chief Physician, Department of Gastroenterology, Xianyang Hospital, Yan’an University, Wenjin New Town Residential Area, Yingbin Avenue, Weicheng District, Xianyang 712000, Shaanxi Province, China. zhangliyun0301111@163.com

Received: March 5, 2024
Revised: April 26, 2024
Accepted: May 14, 2024
Published online: June 27, 2024
Processing time: 116 Days and 22.4 Hours

Core Tip

Core Tip: This study identified the following highlights. The objective response rate in the study was 80.00%, which was significantly higher than that of the control group (57.78%). In the study group, 75.56% of the tumors were resected, which was significantly higher than that of the control group (57.78%). There were 15.56% adverse reactions in the study group and 35.56% in the control group. These differences were statistically significant between the two groups.