Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Apr 27, 2024; 16(4): 1008-1016
Published online Apr 27, 2024. doi: 10.4240/wjgs.v16.i4.1008
Relationship between Helicobacter pylori infection and colorectal polyp/colorectal cancer
Ying Liu, Ding-Quan Yang, Jun-Nan Jiang, Yan Jiao
Ying Liu, Department of General Surgery, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun 130021, Jilin Province, China
Ding-Quan Yang, Jun-Nan Jiang, Department of Gastrointestinal and Colorectal Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, China
Yan Jiao, Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China
Author contributions: Liu Y contributed to the writing, editing of the manuscript and table, and literature search; Yang DQ contributed to the discussion, design of the manuscript and literature search; Jiang JN contributed to the discussion and design of the manuscript; and Jiao Y designed the overall concept and outline of the manuscript.
Supported by the Health Science and Technology Capacity Improvement Project of Health Commission of Jilin Provincial, No. 2023JC016.
Conflict-of-interest statement: The authors have claimed no conflict of interests.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan Jiao, MD, PhD, Surgeon, Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun 130021, Jilin Province, China. lagelangri1@126.com
Received: January 10, 2024
Peer-review started: January 10, 2024
First decision: January 27, 2024
Revised: February 1, 2024
Accepted: March 13, 2024
Article in press: March 13, 2024
Published online: April 27, 2024
Core Tip

Core Tip:Helicobacter pylori (H. pylori) infection is a significant risk factor for colorectal adenomatous polyp (CAP) or colorectal cancer (CRC), and it may contribute to the development of CRC via an inflammatory response, gastrin stimulation, intestinal flora modulation, and virulence factor invasion. In contrast, the diagnosis of CAP may independently predict the probability of H. pylori infection after colon polyp removal.