Meta-Analysis
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jan 27, 2024; 16(1): 205-214
Published online Jan 27, 2024. doi: 10.4240/wjgs.v16.i1.205
Unraveling the efficacy network: A network meta-analysis of adjuvant external beam radiation therapy methods after hepatectomy
Gao-Yuan Yang, Zhi-Wei He, Yong-Chang Tang, Feng Yuan, Ming-Bo Cao, Yu-Peng Ren, Yu-Xuan Li, Xiao-Rui Su, Zhi-Cheng Yao, Mei-Hai Deng
Gao-Yuan Yang, Zhi-Wei He, Ming-Bo Cao, Yu-Peng Ren, Yu-Xuan Li, Xiao-Rui Su, Mei-Hai Deng, Department of Hepatobiliary Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, Guangdong Province, China
Yong-Chang Tang, Department of General Surgery, Qilu Hospital, Shandong University, Jinan 250012, Shandong Province, China
Feng Yuan, Department of General Surgery, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou 511436, Guangdong Province, China
Zhi-Cheng Yao, Department of Hepatobiliary and Pancreatic Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, Guangdong Province, China
Co-first authors: Gao-Yuan Yang and Zhi-Wei He.
Co-corresponding authors: Zhi-Cheng Yao and Mei-Hai Deng.
Author contributions: Yao ZC, and Deng MH contributed to the study design, formal analysis, and writing – original draft; Yang GY, He ZW, Tang YC, and Yuan F contributed to the literature research; Ren YP and Li YX contributed to the data acquisition and curation; Yang GY, Cao MB, and Su XR contributed to the writing – review and editing; all authors contributed to the article and approved the submitted version. It is worth noting that Yao ZC and Deng MH made equal contributions to the research design and supervision, so they are listed as the co-corresponding authors. Yang GY and He ZW made equal contributions to the collection, organization and analysis of data and the writing of the manuscript, so they are listed as the co-first authors.
Supported by The Science and Technology Plan Project of Guangzhou, No. 202102010171; National Natural Science Foundation Cultivation Project of The Third Affiliated Hospital of Sun Yat-sen University, No. 2020GZRPYMS11; Natural Science Foundation of Guangdong Province, No. 2018A030313641; and CSCO-Roche Joint Cancer Research Fund, No. Y-Roche2019/2-0041.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhi-Cheng Yao, PhD, Doctor, Department of Hepatobiliary and Pancreatic Surgery, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Tianhe District, Guangzhou 510630, Guangdong Province, China. yaozhch2@mail.sysu.edu.cn
Received: August 28, 2023
Peer-review started: August 28, 2023
First decision: November 24, 2023
Revised: December 9, 2023
Accepted: January 9, 2024
Article in press: January 9, 2024
Published online: January 27, 2024
Core Tip

Core Tip: The core focus of this study is the comparative analysis of various adjuvant external beam radiation therapy (RT) methods following hepatectomy based on the network meta-analysis. The key aspects emphasized in the study include the efficacy of different RT methods in terms of disease-free survival and overall survival for postoperative liver cancer patients. The research aims to provide valuable insights for future investigations and clinical applications, potentially influencing the direction of liver cancer treatment.