Published online Jan 27, 2024. doi: 10.4240/wjgs.v16.i1.155
Peer-review started: November 30, 2023
First decision: December 18, 2023
Revised: December 21, 2023
Accepted: January 5, 2024
Article in press: January 5, 2024
Published online: January 27, 2024
Core Tip: Postoperative liver failure in hepatocellular carcinoma is a serious complication that seriously affects the survival and quality of life of patients. Our work showed that neutrophil-lymphocyte ratio, fibrosis index based on four factors, and aspartate aminotransferase-to-platelet ratio index independently influenced the occurrence of liver failure following hepatectomy in patients with hepatocellular carcinoma. The column-line graph prediction model constructed in this study for the occurrence of liver failure after hepatectomy in patients with hepatocellular carcinoma showed good predictive ability, and the consistency between the predicted and actual events was high. This model has broad potential as a tool to prevent liver failure after hepatectomy in patients with hepatocellular carcinoma.