Kuang TZ, Xiao M, Liu YF. Predictive value of NLR, Fib4, and APRI in the occurrence of liver failure after hepatectomy in patients with hepatocellular carcinoma. World J Gastrointest Surg 2024; 16(1): 155-165 [PMID: 38328329 DOI: 10.4240/wjgs.v16.i1.155]
Corresponding Author of This Article
Yong-Fan Liu, MM, PhD, Associate Chief Physician, Department of Hepatobiliary Surgery, Ji’an Central People’s Hospital, No. 106 Jinggangshan Avenue, Ji’an 343000, Jiangxi Province, China. lyfsh268@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Jan 27, 2024; 16(1): 155-165 Published online Jan 27, 2024. doi: 10.4240/wjgs.v16.i1.155
Predictive value of NLR, Fib4, and APRI in the occurrence of liver failure after hepatectomy in patients with hepatocellular carcinoma
Tian-Zuo Kuang, Meng Xiao, Yong-Fan Liu
Tian-Zuo Kuang, Meng Xiao, Yong-Fan Liu, Department of Hepatobiliary Surgery, Ji’an Central People’s Hospital, Ji’an 343000, Jiangxi Province, China
Author contributions: Kuang TZ contributed to investigation, software, data curation, formal analysis, and writing-original draft; Xiao M contributed to methodology, supervision, and validation; Liu YF contributed to conceptualization, resources, writing-review, and editing.
Institutional review board statement: The study was reviewed and approved by the Medical Ethics Committee of Ji’an Central People’s Hospital. Institutional Review Board (Approval No. 2021-L121201).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yong-Fan Liu, MM, PhD, Associate Chief Physician, Department of Hepatobiliary Surgery, Ji’an Central People’s Hospital, No. 106 Jinggangshan Avenue, Ji’an 343000, Jiangxi Province, China. lyfsh268@163.com
Received: November 30, 2023 Peer-review started: November 30, 2023 First decision: December 18, 2023 Revised: December 21, 2023 Accepted: January 5, 2024 Article in press: January 5, 2024 Published online: January 27, 2024 Processing time: 55 Days and 21.4 Hours
Core Tip
Core Tip: Postoperative liver failure in hepatocellular carcinoma is a serious complication that seriously affects the survival and quality of life of patients. Our work showed that neutrophil-lymphocyte ratio, fibrosis index based on four factors, and aspartate aminotransferase-to-platelet ratio index independently influenced the occurrence of liver failure following hepatectomy in patients with hepatocellular carcinoma. The column-line graph prediction model constructed in this study for the occurrence of liver failure after hepatectomy in patients with hepatocellular carcinoma showed good predictive ability, and the consistency between the predicted and actual events was high. This model has broad potential as a tool to prevent liver failure after hepatectomy in patients with hepatocellular carcinoma.
