Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Sep 27, 2023; 15(9): 2021-2031
Published online Sep 27, 2023. doi: 10.4240/wjgs.v15.i9.2021
Risk factors for myocardial injury during living donor liver transplantation in pediatric patients with biliary atresia
Yu-Li Wu, Tian-Ying Li, Xin-Yuan Gong, Lu Che, Ming-Wei Sheng, Wen-Li Yu, Yi-Qi Weng
Yu-Li Wu, The First Central Clinical School, Tianjin Medical University, Tianjin 300192, China
Tian-Ying Li, School of Medicine, Nankai University, Tianjin 300071, China
Xin-Yuan Gong, Department of Science and Education, Tianjin First Central Hospital, Tianjin 300192, China
Lu Che, Ming-Wei Sheng, Wen-Li Yu, Yi-Qi Weng, Department of Anesthesiology, Tianjin First Central Hospital, Tianjin 300192, China
Author contributions: Wu YL and Weng YQ helped to write the manuscript; Li TY and Che L coordinated and supervised data collection; Gong XY performed the statistical analysis; Wu YL and Li TY created the tables and figures. Sheng MW revised the manuscript in detail; Weng YQ and Yu WL critically reviewed the manuscript for important intellectual content; Both Weng YQ and Yu WL were responsible for the study and contributed equally to this manuscript; all authors have read and agreed to the publication of the manuscript.
Supported by Science and Technology Foundation of Tianjin Health Bureau, No. ZC20052; Tianjin Key Medical Discipline (Specialty) Construction Project, No. TJYXZDXK-045A; Tianjin Anesthesia Research Development Program of Bethune Charitable Foundation, No. TJMZ2022-005; Natural Science Foundation of Tianjin, No. 21JCQNJC01730; and Young Talent Program of Tianjin First Central Hospital.
Institutional review board statement: The study was reviewed and approved by the ethics committee of the Tianjin First Central Hospital, No. 2022DZX02.
Informed consent statement: Informed consent was waived by the local ethics committee, given the study's retrospective nature.
Conflict-of-interest statement: The authors declare no conflict of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yi-Qi Weng, Doctor, PhD, Chief Physician, Professor, Department of Anesthesiology, Tianjin First Central Hospital, No. 24 Fukang Road, Nankai District, Tianjin 300192, China. wyq2023@nankai.edu.cn
Received: June 23, 2023
Peer-review started: June 23, 2023
First decision: July 4, 2023
Revised: July 10, 2023
Accepted: July 27, 2023
Article in press: July 27, 2023
Published online: September 27, 2023
Processing time: 91 Days and 0.4 Hours
Core Tip

Core Tip: This is a retrospective study to investigate data for children who underwent living donor liver transplantation to determine risk factors for intraoperative myocardial injury. Myocardial injury during liver transplantation is associated with postoperative adverse outcomes in pediatric patients; it can increase the incidence of postoperative mortality. Our findings demonstrated that a high pediatric end-stage liver disease score, a long anhepatic phase duration, and the occurrence of intraoperative postreperfusion syndrome are independent risk factors for myocardial injury.