Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jul 27, 2023; 15(7): 1542-1548
Published online Jul 27, 2023. doi: 10.4240/wjgs.v15.i7.1542
Reoperation for heterochronic intraductal papillary mucinous neoplasm of the pancreas after bile duct neoplasm resection: A case report
Gang Xiao, Tao Xia, Yi-Ping Mou, Yu-Cheng Zhou
Gang Xiao, Department of Hepatopancreatobiliary Surgery, Shaoxing People’s Hospital, Shaoxing 312000, Zhejiang Province, China
Tao Xia, Yi-Ping Mou, Yu-Cheng Zhou, Division of Gastrointestinal and Pancreatic Surgery, Department of General Surgery, Zhejiang Provincial People’s Hospital (People’s Hospital of Hangzhou Medical College), Key Laboratory of Gastroenterology of Zhejiang Province, Hangzhou 310014, Zhejiang Province, China
Author contributions: Xiao G, Xia T, and Mou YP assembled, analyzed, and interpreted the patient’s data and case presentation; Mou YP and Zhou YC reviewed the literature; Xiao G and Mou YP prepared the original manuscript; Mou YP edited and critically revised the manuscript; all authors contributed to writing the manuscript; and all authors read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yi-Ping Mou, MD, Chief & Chairman, Division of Gastrointestinal and Pancreatic Surgery, Department of General Surgery, Zhejiang Provincial People’s Hospital (People’s Hospital of Hangzhou Medical College), Key Laboratory of Gastroenterology of Zhejiang Province, No. 158 Shangtang Road, Gongshu District, Hangzhou 310014, Zhejiang Province, China. yipingmou@126.com
Received: March 24, 2023
Peer-review started: March 28, 2023
First decision: April 14, 2023
Revised: April 28, 2023
Accepted: May 11, 2023
Article in press: May 11, 2023
Published online: July 27, 2023
Processing time: 119 Days and 7.2 Hours
Core Tip

Core Tip: We report a rare case of heterochronous onset of malignant intraductal papillary neoplasm of the bile duct (IPNB) and malignant intraductal papillary mucinous neoplasm of the pancreas (IPMN). The time difference between the onset of the two diseases was 4.5 years. Left hepatectomy and radical pancreaticoduodenectomy were performed with excellent results. This case suggests that IPNB and IPMN are precancerous lesions of low-grade malignancy that require aggressive surgery and long-term postoperative follow-up.