Randomized Controlled Trial
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jul 27, 2023; 15(7): 1474-1484
Published online Jul 27, 2023. doi: 10.4240/wjgs.v15.i7.1474
Transcutaneous electrical acupoint stimulation in adult patients receiving gastrectomy/colorectal resection: A randomized controlled trial
Yuan-Tao Hou, Yuan-Yuan Pan, Lei Wan, Wen-Sheng Zhao, Ying Luo, Qi Yan, Yi Zhang, Wei-Xin Zhang, Yun-Chang Mo, Lu-Ping Huang, Qin-Xue Dai, Dan-Yun Jia, Ai-Ming Yang, Hai-Yan An, An-Shi Wu, Ming Tian, Jian-Qiao Fang, Jun-Lu Wang, Yi Feng
Yuan-Tao Hou, Qi Yan, Yi Zhang, Wei-Xin Zhang, Hai-Yan An, Yi Feng, Department of Anesthesiology, Peking University People’s Hospital, Beijing 100044, China
Yuan-Yuan Pan, Yun-Chang Mo, Lu-Ping Huang, Qin-Xue Dai, Dan-Yun Jia, Jun-Lu Wang, Department of Anesthesiology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China
Lei Wan, Ming Tian, Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
Wen-Sheng Zhao, Department of Pain Medicine, Zhejiang Chinese Medicine and Western Medicine Integrated Hospital, Hangzhou 310003, Zhejiang Province, China
Ying Luo, An-Shi Wu, Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China
Ai-Ming Yang, Department of Anesthesiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Jian-Qiao Fang, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China
Yi Feng, Department of Pain Medicine, Peking University People’s Hospital, Beijing 100044, China
Yi Feng, Key Laboratory for Neuroscience, Ministry of Education/National Health Commission of China, Peking University, Beijing 100083, China
Author contributions: Feng Y, Wang JL, Fang JQ, Tian M, Wu AS, and An HY were responsible for conceptualization and methodology and are joint corresponding authors; Hou YT, Pan YY, Wan L, Zhao WS, Luo Y, and Yan Q collected the data, performed formal analysis, and contributed equally as first authors to this work; Feng Y was responsible for funding acquisition; Zhang Y, Zhang WX, Mo YC, Huang LP, Dai QX, Jia DY, and Yang AM were responsible for project administration; Hou YT wrote the original draft; Feng Y, Wang JL, Fang JQ, Tian M, and Wu AS reviewed and edited the manuscript; All authors read and approved the final manuscript.
Supported by National Basic Research Program of China (Project 973) from The Ministry of Science and Technology of the People's Republic of China, No. 2013CB531900.
Institutional review board statement: This trial was approved by the Ethics Committee of Peking University People’s Hospital on June 9, 2013 and by the Ethical Committees of all participating centers, No. 2013 (09).
Clinical trial registration statement: The trial was registered on the Chinese Clinical Trial Registry, No. ChiCTR-TRC-14004435.
Informed consent statement: Written informed consent was obtained from all participants.
Conflict-of-interest statement: All the authors report having no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yi Feng, MD, PhD, Professor, Department of Anesthesiology, Peking University People’s Hospital, No. 11 Xizhimen South Street, Beijing 100044, China. doctor_yifeng@sina.com
Received: November 23, 2022
Peer-review started: November 23, 2022
First decision: February 23, 2023
Revised: March 5, 2023
Accepted: May 8, 2023
Article in press: May 8, 2023
Published online: July 27, 2023
Core Tip

Core Tip: Transcutaneous electrical acupoint stimulation at an alternating 2/100-Hz frequency and maximum tolerable current to the bilateral Neiguan (P6), Hegu (LI4), Zusanli (ST36), and Sanyinjiao (SP6) did not promote functional recovery of the gastrointestinal tract after major abdominal surgery but alleviated postoperative pain.