Zhang YW, Li Y, Huang WB, Wang J, Qian XE, Yang Y, Huang CS. Utilization of deep neuromuscular blockade combined with reduced abdominal pressure in laparoscopic radical gastrectomy for gastric cancer: An academic perspective. World J Gastrointest Surg 2023; 15(7): 1405-1415 [PMID: 37555115 DOI: 10.4240/wjgs.v15.i7.1405]
Corresponding Author of This Article
Chang-Shun Huang, MBChB, Chief Doctor, Department of Anesthesiology, Ningbo First Hospital, No. 59 Liuting Street, Haishu District, Ningbo 315016, Zhejiang Province, China. nbhcs1967@163.com
Research Domain of This Article
Surgery
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Jul 27, 2023; 15(7): 1405-1415 Published online Jul 27, 2023. doi: 10.4240/wjgs.v15.i7.1405
Utilization of deep neuromuscular blockade combined with reduced abdominal pressure in laparoscopic radical gastrectomy for gastric cancer: An academic perspective
Yi-Wei Zhang, Yong Li, Wan-Bo Huang, Jue Wang, Xing-Er Qian, Yu Yang, Chang-Shun Huang, Department of Anesthesiology, Ningbo First Hospital, Ningbo 315016, Zhejiang Province, China
Author contributions: Zhang YW and Li Y designed the study, contributed equally to this study, are considered as co-first authors; Zhang YW, Li Y, Huang WB, Wang J, and Qian XE conducted the research; Yang Y contributed to the analytical tools; Zhang YW, Li Y and Huang CS analyzed the data and wrote the manuscript; and all authors read and approved the final manuscript.
Supported byZhejiang Health Science and Technology Plan 2022, No. 2022KY320.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the First Hospital of Ningbo (Ethical approval number: 2019R006).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There are no potential conflicts of interest.
Data sharing statement: Raw data and statistics are available from the corresponding author.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chang-Shun Huang, MBChB, Chief Doctor, Department of Anesthesiology, Ningbo First Hospital, No. 59 Liuting Street, Haishu District, Ningbo 315016, Zhejiang Province, China. nbhcs1967@163.com
Received: March 14, 2023 Peer-review started: March 14, 2023 First decision: April 7, 2023 Revised: April 20, 2023 Accepted: June 2, 2023 Article in press: June 2, 2023 Published online: July 27, 2023 Processing time: 129 Days and 5.1 Hours
Core Tip
Core Tip: Laparoscopic radical gastrectomy is a common operation for the treatment of gastric cancer (GC) with minimally invasive and rapid recovery. However, high pneumoperitoneum pressure during laparoscopic surgery has an adverse effect on the perioperative outcome of patients, especially in elderly patients. Deep muscle relaxation has been proved to improve the conditions of abdominal surgery and reduce postoperative pain, but it is still unclear whether deep muscle relaxation combined with low pneumoperitoneum pressure is effective in laparoscopic radical resection of GC in the elderly. In this study, we analyzed the role of deep muscle relaxation combined with low pneumoperitoneum pressure in elderly patients undergoing laparoscopic radical gastrectomy for GC and its effect on inflammation, in order to provide a reference for clinicians to choose treatment options.
