Meta-Analysis
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jun 27, 2023; 15(6): 1202-1210
Published online Jun 27, 2023. doi: 10.4240/wjgs.v15.i6.1202
Efficacy of transanal drainage tube in preventing anastomotic leakage after surgery for rectal cancer: A meta-analysis
Shiki Fujino, Masayoshi Yasui, Masayuki Ohue, Norikatsu Miyoshi
Shiki Fujino, Norikatsu Miyoshi, Innovative Oncology Research and Regenerative Medicine, Osaka International Cancer Institute, Osaka 541-8567, Japan
Masayoshi Yasui, Masayuki Ohue, Department of Surgery, Osaka International Cancer Institute, Osaka 541-8567, Japan
Author contributions: Fujino S, Yasui M, Ohue M, and Miyoshi N designed the research study; Fujino S, Yasui M, and Miyoshi N performed the research; Fujino S and Miyoshi N analyzed the data; Fujino S wrote the manuscript; and all authors have read and approve the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Norikatsu Miyoshi, FACS, FASCRS, FICS, MD, PhD, Assistant Professor, Innovative Oncology Research and Regenerative Medicine, Osaka International Cancer Institute, 3-1-69, Otemae, Chuo-ku, Osaka 541-8567, Japan. nmiyoshi@gesurg.med.osaka-u.ac.jp
Received: December 26, 2022
Peer-review started: December 26, 2022
First decision: February 21, 2023
Revised: March 21, 2023
Accepted: April 25, 2023
Article in press: April 25, 2023
Published online: June 27, 2023
Processing time: 171 Days and 10.8 Hours
Core Tip

Core Tip: Anastomotic leakage (AL) following rectal cancer surgery is a serious problem, and a transanal drainage tube (TDT) is expected to reduce AL. However, the preventive effects of TDT placement are controversial. Thus, we performed a meta-analysis of three randomized controlled trials and two prospective cohort studies. A systematic literature search was performed, and the results of the meta-analysis were synthesized using the Mantel-Haenszel random-effects model. Overall, TDT did not significantly reduce the symptomatic AL rate, but it did among patients without a diverting stoma.