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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Apr 27, 2023; 15(4): 664-673
Published online Apr 27, 2023. doi: 10.4240/wjgs.v15.i4.664
Published online Apr 27, 2023. doi: 10.4240/wjgs.v15.i4.664
Computed tomography perfusion in differentiating portal hypertension: A correlation study with hepatic venous pressure gradient
Jian Dong, Chun-Yan Zhang, Department of Radiology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
Yu Zhang, Yi-Fan Wu, Zhen-Dong Yue, Zhen-Hua Fan, Fu-Quan Liu, Lei Wang, Department of Interventional Radiology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
Author contributions: Dong J, Liu FQ and Wang L designed the report; Zhang Y, Wu YF, Yue ZD, and Fan ZH collected the clinical data; Wang L and Zhang CY analyzed the data and wrote the paper; Dong J and Liu FQ performed quality control; Liu FQ contributed to administrative and financial support.
Supported by the National Natural Science Foundation of China General Program , No. 81871461 .
Institutional review board statement: This study was approved by the Ethics Committee of the Beijing Shijitan Hospital, Capital Medical University (No. 201801).
Clinical trial registration statement: This study is registered at ClinicalTrials.gov, registration number ChiCTR1800015268 (https://www.chictr.org.cn/showproj.aspx?proj=26048).
Informed consent statement: Written informed consent was obtained from each patient.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lei Wang, MD, Doctor, Department of Interventional Radiology, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tieyi Street, Haidian District, Beijing 100038, China. wanglei800212@126.com
Received: December 20, 2022
Peer-review started: December 20, 2022
First decision: January 9, 2023
Revised: January 11, 2023
Accepted: March 23, 2023
Article in press: March 23, 2023
Published online: April 27, 2023
Processing time: 123 Days and 21.7 Hours
Peer-review started: December 20, 2022
First decision: January 9, 2023
Revised: January 11, 2023
Accepted: March 23, 2023
Article in press: March 23, 2023
Published online: April 27, 2023
Processing time: 123 Days and 21.7 Hours
Core Tip
Core Tip: Transjugular intrahepatic portosystemic shunt (TIPS) is an effective therapy for portal hypertension (PH) related gastro-esophageal variceal bleeding (GEVB). However, the decrease of liver blood supply after TIPS led to a decline in the liver detoxification, which increased potential risk for the occurrence of various complications such as hepatic encephalopathy, liver dysfunction and even liver failure. This study explored the feasibility of computed tomography perfusion imaging in quantitatively evaluating the changes in liver and spleen blood supply in PH related GEVB before and after TIPS, and making correlation analysis between perfusion parameters, hepatic venous pressure gradient and Child-Pugh scores were evaluated.