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World J Gastrointest Surg. Apr 27, 2023; 15(4): 553-565
Published online Apr 27, 2023. doi: 10.4240/wjgs.v15.i4.553
The spectrum of pneumatosis intestinalis in the adult. A surgical dilemma
Giuseppe Tropeano, Marta Di Grezia, Caterina Puccioni, Valentina Bianchi, Gilda Pepe, Valeria Fico, Gaia Altieri, Giuseppe Brisinda
Giuseppe Tropeano, Marta Di Grezia, Caterina Puccioni, Valentina Bianchi, Gilda Pepe, Valeria Fico, Gaia Altieri, Giuseppe Brisinda, Emergency Surgery and Trauma Center, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome 00168, Italy
Giuseppe Brisinda, Department of Surgery, Università Cattolica del Sacro Cuore, Rome 00168, Italy
Author contributions: Tropeano G and Di Grezia M equally contributed to the drafting of the manuscript and must both be considered first author; Tropeano G, Di Grezia M, Puccioni C, Bianchi V and Brisinda G designed the research; Bianchi V, Pepe G, Fico V and Altieri G performed the research and selected the articles; Tropeano G, Di Grezia M and Puccioni C analyzed the data; Tropeano G, Di Grezia M, Puccioni C and Brisinda G reviewed the selected manuscripts and wrote the paper; All the authors read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Giuseppe Brisinda, MD, Professor, Surgeon, Emergency Surgery and Trauma Center, Fondazione Policlinico Universitario A Gemelli IRCCS, Largo Agostino Gemelli 8, Rome 00168, Rome, Italy. gbrisin@tin.it
Received: December 7, 2022
Peer-review started: December 7, 2022
First decision: February 8, 2023
Revised: February 10, 2023
Accepted: March 21, 2023
Article in press: March 21, 2023
Published online: April 27, 2023
Processing time: 136 Days and 23.8 Hours
Core Tip

Core Tip: Pneumatosis intestinalis (PI) represents a radiological diagnosis that must be understood correctly in order to follow the appropriate management. It is essential to identify the conditions that can evolve into transmural intestinal ischemia. It is also important to recognize those cases where PI can be managed conservatively. The integration of the clinical presentation, laboratory tests and abnormal abdominal physical examination can give indications on the path to follow. With this narrative review we have tried to provide a comprehensive analysis of the knowledge of this topic by proposing an algorithm to guide clinical decisions.