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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Mar 27, 2023; 15(3): 440-449
Published online Mar 27, 2023. doi: 10.4240/wjgs.v15.i3.440
Published online Mar 27, 2023. doi: 10.4240/wjgs.v15.i3.440
Endoscopic mucosal resection with double band ligation versus endoscopic submucosal dissection for small rectal neuroendocrine tumors
Jia-Lan Huang, Ri-Yun Gan, Ze-Han Chen, Department of Gastroenterology, The Second Clinical Medical College, Jinan University, Shenzhen 518020, Guangdong Province, China
Ruo-Yu Gao, Department of Gastroenterology, Shenzhen Luohu People's Hospital, Shenzhen 518020, Guangdong Province, China
De-Feng Li, Li-Sheng Wang, Jun Yao, Department of Gastroenterology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong Province, China
Author contributions: Yao J was responsible for design of the study and reviewed the manuscript; Huang JL drafted the manuscript; Huang JL, Gan RY, Chen ZH and Gao RY contributed to data acquisition, analysis, and interpretation; Yao J, Li DF and Wang LS were responsible for revising manuscript; All authors have read and approved the final manuscript.
Supported by Technical Research and Development Project of Shenzhen, No. JCYJ20210324113215040.
Institutional review board statement: The study was reviewed and approved by the ethics committee of Shenzhen People's Hospital (Approval No. LL-KY-2022152-01).
Clinical trial registration statement: This study is registered at Chinese Clinical Trial Registry. The registration identification number is ChiCTR2200063871.
Informed consent statement: All study participants provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at yao.jun@szhospital.com. Participants gave informed consent for data sharing.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jun Yao, MD, PhD, Associate Chief Physician, Associate Professor, Department of Gastroenterology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), 1017 East Gate Road, Shenzhen 518020, Guangdong Province, China.
Received: December 6, 2022
Peer-review started: December 6, 2022
First decision: December 27, 2022
Revised: January 9, 2023
Accepted: February 27, 2023
Article in press: February 27, 2023
Published online: March 27, 2023
Processing time: 110 Days and 22.7 Hours
Peer-review started: December 6, 2022
First decision: December 27, 2022
Revised: January 9, 2023
Accepted: February 27, 2023
Article in press: February 27, 2023
Published online: March 27, 2023
Processing time: 110 Days and 22.7 Hours
Core Tip
Core Tip: Endoscopic mucosal resection (EMR) with double band ligation (EMR-dB), a simplified modification of EMR with band ligation, is an alternative strategy to remove small rectal neuroendocrine tumors (NETs). Our study first evaluates the feasibility and safety of EMR-dB and endoscopic submucosal dissection (ESD) for the treatment of small rectal NETs (≤ 10 mm). We discovered that the EMR-dB technique took less time than ESD, and displayed a similar curative effect to ESD. If no lymph nodes and distant metastases are revealed by either endoscopic ultrasound or computerized tomography, EMR-dB is a feasible and safe option for the treatment of small rectal NETs.