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World J Gastrointest Surg. Mar 27, 2023; 15(3): 323-337
Published online Mar 27, 2023. doi: 10.4240/wjgs.v15.i3.323
Current trends in perioperative treatment of resectable gastric cancer
İbrahim Yıldız, Leyla Özer, Elif Şenocak Taşçı, İbrahim Vedat Bayoglu, Erman Aytac
İbrahim Yıldız, Leyla Özer, Department of Medical Oncology, Acıbadem MAA University, İstanbul 34567, Turkey
Elif Şenocak Taşçı, Department of Medical Oncology, Acıbadem University, İstanbul 34567, Turkey
İbrahim Vedat Bayoglu, Department of Medical Oncology, Marmara University, İstanbul 12345, Turkey
Erman Aytac, Department of Surgery, Acibadem University School of Medicine, Istanbul 34567, Turkey
Author contributions: Yıldız İ wrote the paper; Özer L, Şenocak Taşçı E and Aytac E collected the data; Bayoglu İV prepared the figure and tables.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Leyla Özer, MD, Associate Professor, Department of Medical Oncology, Acıbadem MAA University, Halkalı Merkez, Turgut Özal Bulvarı No:16, Küçükçekmece/ İstanbul, İstanbul 34567, Turkey. leyla.ozer@acibadem.com
Received: October 28, 2022
Peer-review started: October 28, 2022
First decision: November 30, 2022
Revised: January 5, 2023
Accepted: February 27, 2023
Article in press: February 27, 2023
Published online: March 27, 2023
Processing time: 149 Days and 18.4 Hours
Core Tip

Core Tip: The results of the most recent randomized studies have led to a shift from traditional care concepts towards evidence-based multimodal treatment strategies for gastric cancer (GC). Perioperative chemotherapy has become the standard of care for resectable GC. Molecular-based modifications of the backbone treatment increase the efficacy of therapy.