Review
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Feb 27, 2023; 15(2): 127-141
Published online Feb 27, 2023. doi: 10.4240/wjgs.v15.i2.127
Minimum platelet count threshold before invasive procedures in cirrhosis: Evolution of the guidelines
Marco Biolato, Federica Vitale, Tiziano Galasso, Antonio Gasbarrini, Antonio Grieco
Marco Biolato, Antonio Gasbarrini, Antonio Grieco, Department of Medical and Surgical Sciences, CEMAD, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy
Marco Biolato, Federica Vitale, Tiziano Galasso, Antonio Gasbarrini, Antonio Grieco, Department of Internal Medicine, Catholic University of Sacred Heart, Rome 00168, Italy
Author contributions: Biolato M and Vitale F wrote the paper; Galasso T prepared the tables; Gasbarrini A and Grieco A revised the paper for important intellectual content; All authors read and approved the final manuscript.
Conflict-of-interest statement: Biolato M and Grieco A received personal fees from SOBI s.r.l. and Shionogi B.V. Other authors declare no conflict of interests relevant to this manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Marco Biolato, MD, PhD, Staff Physician, Department of Medical and Surgical Sciences, CEMAD, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo A. Gemelli 8, Rome 00168, Italy. marco.biolato@policlinicogemelli.it
Received: September 27, 2022
Peer-review started: September 27, 2022
First decision: October 30, 2022
Revised: December 9, 2022
Accepted: February 7, 2023
Article in press: February 7, 2023
Published online: February 27, 2023
Processing time: 152 Days and 14.3 Hours
Core Tip

Core Tip: There are several reviews in the literature that deals with the management of thrombocytopenia in patients with cirrhosis undergoing scheduled invasive procedures. However, this review is one of the few to provide a comparison between the main guidelines concerning the platelet-count reference threshold to consider safely performing the various types of procedures.