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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Nov 27, 2023; 15(11): 2413-2422
Published online Nov 27, 2023. doi: 10.4240/wjgs.v15.i11.2413
Published online Nov 27, 2023. doi: 10.4240/wjgs.v15.i11.2413
Effects of cytoreductive surgery combined with hyperthermic perfusion chemotherapy on prognosis of patients with advanced gallbladder cancer
Jin-Xiu Wu, Li Yao, Department of Hepatobiliary-Pancreatic Surgery, Punan Branch of Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200125, China
Rong Hua, Department of Biliary-Pancreatic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
Xiang-Ji Luo, Feng Xie, Department of Biliary Tract Surgery, Eastern Hepatobiliary Surgery Hospital, Secondary Military Medical University, Shanghai 200438, China
Author contributions: Wu JX, Yao L, and Hua R designed the manuscript; Wu JX performed the study and wrote the manuscript; Yao L supervised the report writing; Hua R contributed to the analysis; Luo XJ and Xie F supervised the report.
Supported by Shanghai Pudong New Area Health Commission’s Excellent Young Medical Talent Training Plan , No. PWRq2020-68 ; Shanghai Pudong New Area Health Commission Discipline Leader Training Project , No. PWRd2020-16 ; and Shanghai Pudong New Area Science and Technology Development Fund , No. PKJ2020-Y36 .
Institutional review board statement: The Punan Branch of Renji Hospital, Shanghai Jiao Tong University School of Medicine reviewed and approved this study.
Informed consent statement: All study participants and their legal guardians provided written informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The dataset is available from the corresponding author at yaolibestpn@sina.com.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li Yao, MM, Associate Chief Physician, Department of Hepatobiliary-Pancreatic Surgery, Punan Branch of Renji Hospital, Shanghai Jiao Tong University School of Medicine, No. 279 Linyi Road, Pudong District, Shanghai 200125, China.
Received: June 26, 2023
Peer-review started: June 26, 2023
First decision: July 17, 2023
Revised: July 24, 2023
Accepted: August 15, 2023
Article in press: August 15, 2023
Published online: November 27, 2023
Processing time: 154 Days and 2.3 Hours
Peer-review started: June 26, 2023
First decision: July 17, 2023
Revised: July 24, 2023
Accepted: August 15, 2023
Article in press: August 15, 2023
Published online: November 27, 2023
Processing time: 154 Days and 2.3 Hours
Core Tip
Core Tip: This study explores the potential benefits of combining cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in treating gallbladder cancer (GC). Our results show that this combined approach may increase the median overall survival and three-year survival rates, and may decrease the incidence of postoperative complications. While the results are promising, this represents a step forward in GC treatment and suggests a possible new therapeutic strategy that warrants further investigation.