Systematic Reviews
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Oct 27, 2023; 15(10): 2305-2319
Published online Oct 27, 2023. doi: 10.4240/wjgs.v15.i10.2305
Hepatobiliary tuberculosis in the developing world
Ma Jenina Angela Esguerra-Paculan, Jonathan Soldera
Ma Jenina Angela Esguerra-Paculan, Jonathan Soldera, Acute Medicine, University of South Wales, Cardiff CF37 1DL, United Kingdom
Author contributions: Esguerra-Paculan MJA and Soldera J participated in the concept and design research, drafted the manuscript and contributed to data acquisition, analysis and interpretation; Soldera J contributed to study supervision; all authors contributed to critical revision of the manuscript for important intellectual content.
Conflict-of-interest statement: The authors have no conflict of interest to disclose.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jonathan Soldera, MD, MSc, Associate Professor, Staff Physician, Acute Medicine, University of South Wales, Llantwit Road, Pontypridd, Cardiff CF37 1DL, United Kingdom. jonathansoldera@gmail.com
Received: July 3, 2023
Peer-review started: July 3, 2023
First decision: July 18, 2023
Revised: July 31, 2023
Accepted: August 15, 2023
Article in press: August 15, 2023
Published online: October 27, 2023
Processing time: 116 Days and 9.1 Hours
Core Tip

Core Tip: Hepatobiliary tuberculosis presents diagnostic challenges due to its similarity to other conditions, emphasizing the need for timely and accurate diagnosis. This systematic review of 24 cases highlights the common symptoms, diagnostic procedures, and treatment outcomes. Fever, abdominal pain, weight loss, and jaundice were the most frequent symptoms observed. Computed tomography scan and ultrasound were effective diagnostic tools, while histologic confirmation confirmed the presence of Mycobacterium tuberculosis. Treatment with Rifampicin, Isoniazid, Pyrazinamide, and Ethambutol showed positive outcomes in the majority of cases. This study underscores the importance of precise diagnosis and appropriate management to ensure successful recovery and patient safety.