Retrospective Study
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World J Gastrointest Surg. Jun 27, 2022; 14(6): 580-593
Published online Jun 27, 2022. doi: 10.4240/wjgs.v14.i6.580
Prognostic significance of the preoperative hemoglobin to albumin ratio for the short-term survival of gastric cancer patients
Ce-Gui Hu, Bai-E Hu, Jin-Feng Zhu, Zheng-Ming Zhu, Chao Huang
Ce-Gui Hu, Bai-E Hu, Jin-Feng Zhu, Zheng-Ming Zhu, Chao Huang, Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
Author contributions: Hu BE and Hu CG designed the study and contributed equally to this work; Hu BE, Hu CG and Zhu JF collected the clinical data; Hu BE analyzed the data and wrote the manuscript with contributions from all authors; Zhu ZM and Huang C provided critical comments for this paper; All authors read and approved the final version of the paper.
Supported by National Natural Science Foundation of China, No. 81560389; and Key Research and Development Program of Jiangxi Province, No. 20181BBG70015.
Institutional review board statement: The study was reviewed and approved by the Medical Research Ethics Committee of the Second Affiliated Hospital of Nanchang University Institutional Review Board (Approval No. 20191130).
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chao Huang, PhD, Doctor, Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Nanchang University, No. 1 Minde Road, Nanchang 330006, Jiangxi Province, China. huangchao8041@163.com
Received: January 11, 2022
Peer-review started: January 11, 2022
First decision: March 12, 2022
Revised: March 20, 2022
Accepted: May 28, 2022
Article in press: May 28, 2022
Published online: June 27, 2022
Processing time: 166 Days and 22.7 Hours
Core Tip

Core Tip: Hemoglobin and albumin are associated with the prognosis of gastric cancer (GC) patients. However, the prognostic value of the hemoglobin to albumin ratio (HAR) for the short-term survival of GC patients with D2 radical resection has not been studied. HAR was an independent risk factor for the short-term survival of GC patients. GC patients with a low HAR had a poor prognosis. Low HAR was markedly related to high stage, T classification and tumor size. The nomogram model was based on HAR, age, CA19-9, CA125 and stage and can accurately predict the short-term survival of D2 radical resection GC patients.