Meta-Analysis
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Dec 27, 2022; 14(12): 1397-1410
Published online Dec 27, 2022. doi: 10.4240/wjgs.v14.i12.1397
Meta-analysis of transanal vs laparoscopic total mesorectal excision of low rectal cancer: Importance of appropriate patient selection
Pratik Bhattacharya, Ishaan Patel, Noureen Fazili, Shahab Hajibandeh, Shahin Hajibandeh
Pratik Bhattacharya, Department of Surgery, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham B71 4HJ, United Kingdom
Ishaan Patel, Noureen Fazili, Department of Surgery, Queen Elizabeth Hospital Birmingham, Birmingham B15 2GW, United Kingdom
Shahab Hajibandeh, Department of Surgery, University Hospital of Wales, Cardiff CF14 4XW, United Kingdom
Shahin Hajibandeh, Department of Surgery, Royal Stoke University Hospital, Stoke-on-Trent ST4 6QG, United Kingdom
Author contributions: Shahi H designed the research study; Patel I, Bhattacharya P, and Fazili N collected the data for the meta-analysis; Hajibandeh S and Hajibandeh S analysed and interpreted the data, did the statistical analysis, and wrote the article; all authors critically revised the article and provided final approval for the article.
Conflict-of-interest statement: There are no conflicts of interest to report.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shahin Hajibandeh, MD, Senior Researcher, Surgeon, Department of Surgery, Royal Stoke University Hospital, Newcastle Road, Stoke-on-Trent ST4 6QG, United Kingdom. shahin_hajibandeh@yahoo.com
Received: October 2, 2022
Peer-review started: October 2, 2022
First decision: October 30, 2022
Revised: November 6, 2022
Accepted: December 13, 2022
Article in press: December 13, 2022
Published online: December 27, 2022
Processing time: 85 Days and 10.1 Hours
Core Tip

Core Tip: The meta-analysis of best available evidence demonstrated that for low rectal tumours, Transanal total mesorectal excision (TaTME) is associated with better clinical and short term oncological outcomes compared to Laparoscopic TME. More randomised controlled trials with adequate power and high quality are required to not only confirm these findings, but also to evaluate long term oncological and functional outcomes.