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World J Gastrointest Surg. Aug 27, 2021; 13(8): 756-763
Published online Aug 27, 2021. doi: 10.4240/wjgs.v13.i8.756
Borderline resectable for colorectal liver metastases: Present status and future perspective
Yuki Kitano, Hiromitsu Hayashi, Takashi Matsumoto, Shotaro Kinoshita, Hiroki Sato, Yuta Shiraishi, Yosuke Nakao, Takayoshi Kaida, Katsunori Imai, Yo-ichi Yamashita, Hideo Baba
Yuki Kitano, Hiromitsu Hayashi, Takashi Matsumoto, Shotaro Kinoshita, Hiroki Sato, Yuta Shiraishi, Yosuke Nakao, Takayoshi Kaida, Katsunori Imai, Yo-ichi Yamashita, Hideo Baba, Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, Japan
Author contributions: Kitano Y, Hayashi H, Imai K, Yamashita YI and Baba H contributed conception and design; Kitano Y, Hayashi H, Matsumto T, Kinoshita S, Sato H, Shiraishi Y, Nakao Y, Kaida T, Imai K, Yamashita YI, and Baba H contributed writing, review, and/or revision of the manuscript; Kitano Y, Hayashi H, Imai K, Yamashita YI, and Baba H contributed study supervision.
Conflict-of-interest statement: No conflict of interest exists in this study.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hiromitsu Hayashi, FACS, MD, PhD, Assistant Professor, Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1, Kumamoto 860-8556, Japan. hhayasi@kumamoto-u.ac.jp
Received: January 12, 2021
Peer-review started: January 12, 2021
First decision: March 30, 2021
Revised: April 6, 2021
Accepted: July 6, 2021
Article in press: July 6, 2021
Published online: August 27, 2021
Processing time: 219 Days and 19.5 Hours
Core Tip

Core Tip: At this stage, a clear definition and treatment policy for borderline resectable colorectal liver metastases has not been established. According to previous reports, borderline resectable for colorectal liver metastases is oncologically highly malignant (simultaneous liver metastasis, multiple tumors, large tumor diameter, high level of carcinoembryonic antigen, extrahepatic lesions) or technically difficult (necessity of special procedures such as radiofrequency ablation, portal vein embolization, two-stage hepatectomy, and associating liver partition and portal vein ligation for staged hepatectomy for R0 resection or close to the main vessel), and hepatectomy after preoperative adjuvant chemotherapy is recommended as a treatment policy.