Minireviews
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Nov 27, 2021; 13(11): 1338-1350
Published online Nov 27, 2021. doi: 10.4240/wjgs.v13.i11.1338
Surgical ampullectomy: A comprehensive review
Darren L Scroggie, Vasileios K Mavroeidis
Darren L Scroggie, Department of Population Health Sciences, Bristol Centre for Surgical Research, Bristol Medical School, Bristol BS8 2PS, United Kingdom
Vasileios K Mavroeidis, Department of HPB Surgery, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol Royal Infirmary, Bristol BS2 8HW, United Kingdom
Vasileios K Mavroeidis, Department of Surgery, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, United Kingdom
Author contributions: Scroggie DL drafted the original manuscript and conducted the literature review; Scroggie DL and Mavroeidis VK designed the study, did the literature search, prepared the final draft and approved the final version; Mavroeidis VK conceptualized the study, made critical revisions and provided the images used for illustration.
Conflict-of-interest statement: The authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Vasileios K Mavroeidis, MD, MSc, FRCS, FICS, MFSTEd, Surgeon, Department of HPB Surgery, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol Royal Infirmary, Upper Maudlin Street, Bristol BS2 8HW, United Kingdom. blackbasildr@yahoo.gr
Received: April 18, 2021
Peer-review started: April 18, 2021
First decision: May 13, 2021
Revised: May 29, 2021
Accepted: October 14, 2021
Article in press: October 14, 2021
Published online: November 27, 2021
Processing time: 221 Days and 21.3 Hours
Core Tip

Core Tip: The role of surgical or transduodenal ampullectomy in the management of ampullary lesions has not been well-defined and the available evidence has been entirely observational. However, it appears that suitably selected cases of ampullary tumours may benefit from favourable peri-operative and long-term outcomes with very low mortality and significantly long survival, hence the role of surgical ampullectomy in this setting warrants further clarification, while it can also be useful in the management of specific benign entities. In this comprehensive review, we explore the role of surgical ampullectomy in the modern management of ampullary lesions.