Manesh M, Henry R, Gallagher S, Greas M, Sheikh MR, Zielsdorf S. Hodgkin lymphoma masquerading as perforated gallbladder adenocarcinoma: A case report. World J Gastrointest Surg 2021; 13(10): 1279-1284 [PMID: 34754395 DOI: 10.4240/wjgs.v13.i10.1279]
Corresponding Author of This Article
Reynold Henry, MD, Surgeon, Department of Surgery, University of Southern California, 2051 Marengo Street IPT, C5L100, Los Angeles, CA 90033, United States. reyshenry@gmail.com
Research Domain of This Article
Surgery
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Oct 27, 2021; 13(10): 1279-1284 Published online Oct 27, 2021. doi: 10.4240/wjgs.v13.i10.1279
Hodgkin lymphoma masquerading as perforated gallbladder adenocarcinoma: A case report
Michelle Manesh, Reynold Henry, Shea Gallagher, Michael Greas, Mohd Raashid Sheikh, Shannon Zielsdorf
Michelle Manesh, Reynold Henry, Shea Gallagher, Mohd Raashid Sheikh, Shannon Zielsdorf, Department of Surgery, University of Southern California, Los Angeles, CA 90033, United States
Michael Greas, Department of Pathology, University of Southern California, Los Angeles, CA 90033, United States
Author contributions: Manesh M, Henry R, Gallagher S and Zielsdorf S were the patient’s surgeons, reviewed the literature and contributed to manuscript drafting; Greas M performed the pathologic analyses and interpretation and contributed to manuscript drafting; Sheikh MR was responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Reynold Henry, MD, Surgeon, Department of Surgery, University of Southern California, 2051 Marengo Street IPT, C5L100, Los Angeles, CA 90033, United States. reyshenry@gmail.com
Received: April 20, 2021 Peer-review started: April 20, 2021 First decision: June 24, 2021 Revised: June 24, 2021 Accepted: August 30, 2021 Article in press: August 30, 2021 Published online: October 27, 2021 Processing time: 188 Days and 12.9 Hours
Core Tip
Core Tip: Here we present a case of Hodgkin lymphoma masquerading as gallbladder adenocarcinoma. In our patient, Hodgkin lymphadenopathy in the region of the porta hepatitis led to obstructions of the cystic and common hepatic ducts, causing acute cholecystitis and subsequent gallbladder perforation with associated cholangitis. Our case highlights the importance of histopathological assessment in diagnosing gallbladder malignancy when a patient presents with gallbladder perforation and a grossly positive positron emission tomography/computed tomography scan. For either gallbladder adenocarcinoma or Hodgkin lymphoma, chemotherapy tailored to the disease (and appropriate surgical intervention) are essential to achieve the best chance of cure and long-term survival.
